v1.45.1

• Fix URL code for tissue cache range fetch (#368)

v1.45.0

This release integrates gene-tissue expression visualizations into Ideogram. Data comes from GTEx. Here's how it looks!

Release_1-45-0__IdeogramJS_2024-01-15.mov

Links below -- particularly #365, #366, and #367 -- describe the enhancements in detail.

Changes

• Ensure top max-expressing tissue is shown, robustify curve shift (#367)
• Reframe tissue curves on hover, enriching expression comparison (#366)
• Show gene expression distribution by tissue (#365)
• Enhance gene leads tooltip: plot reference expression by tissue (#364)
• Show top expressed tissues by gene (#363)
• Show if gene is among top expressed in tissue (#362)

v1.44.1

• Fix Gene Leads slowness for pig (#361)

v1.44.0

• Improve accessibility, fix annotsInList parameter (#360)

v1.43.0

• Enable interactive legend (#359)
• Improve transcript navigation, close popover on "Escape" (#358)
• Update to Ensembl 110 and GRCm39; refine protein colors (#357)
• Show signal peptides in protein diagrams (#356)
• Protein diagrams: show unfeatured regions, enlarge (#355)
• Illustrate membrane proteins (#353, #354)
• Clarify sequence features in protein diagrams (#352)
• Add mouse RNA and protein diagrams, update human protein diagrams (#351)
• Refine paralog neighborhoods (#350)
• Refine tooltips for splice toggle and isoform arrows (#349)
• Coarsen fruit fly chromosomes to fix cytoband issues (#348)
• Add Poplar assembly (#346)

v1.42.0

• Find gene by synonym (#343)
• Fix splice bug when 1st UTR and exon exactly align (#337)
• Delete old service worker caches, economize NPM package (#342)
• Refine synonym display, handle rare splicing, refine protein colors (#345)

v1.41.0

• Enable protein diagrams (#334)
• Colored protein diagrams (#335)
• Add minimal example code for gene leads kit (#336)
• Update Jupyter example to fix deprecations (#332)
• Fix rotate-on-click for chromosomes fetched from NCBI (#331)

Here's a video on gene leads ideogram. (Unmute it by clicking the speaker icon at lower right.)

Gene_leads_ideogram__IdeogramJS_2023-01-16.mp4

v1.40.0

• Fix sparse genes in gene leads (#328)
• Fix splice animation for unannotated 5'-UTR in nonsense mediated decay (#327)
• Rebrand "Related genes" to "Gene leads", refine example code (#326)

v1.39.0

• Add UI to select any alternative transcript (#324)
• Refine object constancy, handling of unfound genes, subpart hover text (#323)
• Fix CDS size when on same exon as 3'-UTR (#322)
• Compress all human gene structures into size of smartphone photo (#321)

v1.38.0

• Animate splicing gene transcripts (#320)
• Highlight, navigate, and summarize transcript subparts (#318)
• Enable splicing gene transcripts (#313)
• Enrich TSV parser, related genes configurability (#312)
• Improve offline handling in related genes kit (#311)
• Show gene structure diagrams in tooltips (#309)
• Fix issue with custom organism cytogenetic band files (#308)