diff --git a/yew-macro/tests/macro/html-tag-fail.stderr b/yew-macro/tests/macro/html-tag-fail.stderr
index 1571cb83e14..d13496e52fd 100644
--- a/yew-macro/tests/macro/html-tag-fail.stderr
+++ b/yew-macro/tests/macro/html-tag-fail.stderr
@@ -204,10 +204,10 @@ error[E0308]: mismatched types
   --> $DIR/html-tag-fail.rs:32:20
    |
 32 |     html! { <input onclick=1 /> };
-   |                    ^^^^^^^ expected struct `yew::callback::Callback`, found integer
+   |                    ^^^^^^^ expected enum `yew::callback::Callback`, found integer
    |
-   = note: expected struct `yew::callback::Callback<web_sys::features::gen_MouseEvent::MouseEvent>`
-                found type `{integer}`
+   = note: expected enum `yew::callback::Callback<web_sys::features::gen_MouseEvent::MouseEvent>`
+              found type `{integer}`
    = note: this error originates in a macro (in Nightly builds, run with -Z macro-backtrace for more info)
 
 error[E0308]: mismatched types
@@ -216,8 +216,8 @@ error[E0308]: mismatched types
 33 |     html! { <input onclick=Callback::from(|a: String| ()) /> };
    |                    ^^^^^^^ expected struct `web_sys::features::gen_MouseEvent::MouseEvent`, found struct `std::string::String`
    |
-   = note: expected struct `yew::callback::Callback<web_sys::features::gen_MouseEvent::MouseEvent>`
-              found struct `yew::callback::Callback<std::string::String>`
+   = note: expected enum `yew::callback::Callback<web_sys::features::gen_MouseEvent::MouseEvent>`
+              found enum `yew::callback::Callback<std::string::String>`
    = note: this error originates in a macro (in Nightly builds, run with -Z macro-backtrace for more info)
 
 error[E0599]: no method named `to_string` found for struct `NotToString` in the current scope
diff --git a/yew/src/callback.rs b/yew/src/callback.rs
index 6be69d9c97a..eb466bf39c8 100644
--- a/yew/src/callback.rs
+++ b/yew/src/callback.rs
@@ -1,5 +1,6 @@
-//! This module contains structs to interact with `Scope`s.
+//! This module contains data types for interacting with `Scope`s.
 
+use std::cell::RefCell;
 use std::fmt;
 use std::rc::Rc;
 
@@ -10,36 +11,73 @@ use std::rc::Rc;
 /// Callbacks should be used from JS callbacks or `setTimeout` calls.
 /// </aside>
 /// `Rc` wrapper used to make it clonable.
-pub struct Callback<IN>(Rc<dyn Fn(IN)>);
+pub enum Callback<IN> {
+    /// A callback that can be called multiple times
+    Callback(Rc<dyn Fn(IN)>),
+    /// A callback that will only be called once. Panics if it is called again
+    CallbackOnce(Rc<CallbackOnce<IN>>),
+}
+
+type CallbackOnce<IN> = RefCell<Option<Box<dyn FnOnce(IN)>>>;
 
 impl<IN, F: Fn(IN) + 'static> From<F> for Callback<IN> {
     fn from(func: F) -> Self {
-        Callback(Rc::new(func))
+        Callback::Callback(Rc::new(func))
     }
 }
 
 impl<IN> Clone for Callback<IN> {
     fn clone(&self) -> Self {
-        Callback(self.0.clone())
+        match self {
+            Callback::Callback(cb) => Callback::Callback(cb.clone()),
+            Callback::CallbackOnce(cb) => Callback::CallbackOnce(cb.clone()),
+        }
     }
 }
 
 impl<IN> PartialEq for Callback<IN> {
     fn eq(&self, other: &Callback<IN>) -> bool {
-        Rc::ptr_eq(&self.0, &other.0)
+        match (&self, &other) {
+            (Callback::Callback(cb), Callback::Callback(other_cb)) => Rc::ptr_eq(cb, other_cb),
+            (Callback::CallbackOnce(cb), Callback::CallbackOnce(other_cb)) => {
+                Rc::ptr_eq(cb, other_cb)
+            }
+            _ => false,
+        }
     }
 }
 
 impl<IN> fmt::Debug for Callback<IN> {
     fn fmt(&self, f: &mut fmt::Formatter<'_>) -> fmt::Result {
-        f.write_str("Callback<_>")
+        let data = match self {
+            Callback::Callback(_) => "Callback<_>",
+            Callback::CallbackOnce(_) => "CallbackOnce<_>",
+        };
+
+        f.write_str(data)
     }
 }
 
 impl<IN> Callback<IN> {
     /// This method calls the actual callback.
     pub fn emit(&self, value: IN) {
-        (self.0)(value);
+        match self {
+            Callback::Callback(cb) => cb(value),
+            Callback::CallbackOnce(rc) => {
+                let cb = rc.replace(None);
+                let f = cb.expect("callback in CallbackOnce has already been used");
+                f(value)
+            }
+        };
+    }
+
+    /// Creates a callback from a FnOnce. You are responsible for ensuring
+    /// the callback is only called once otherwise it will panic.
+    pub fn once<F>(func: F) -> Self
+    where
+        F: FnOnce(IN) + 'static,
+    {
+        Callback::CallbackOnce(Rc::new(RefCell::new(Some(Box::new(func)))))
     }
 
     /// Creates a no-op callback which can be used when it is not suitable to use an
diff --git a/yew/src/html/scope.rs b/yew/src/html/scope.rs
index 25b8111beb7..3b57d1c33b7 100644
--- a/yew/src/html/scope.rs
+++ b/yew/src/html/scope.rs
@@ -119,7 +119,7 @@ impl<COMP: Component> Scope<COMP> {
         self.update(ComponentUpdate::MessageBatch(messages));
     }
 
-    /// This method creates a `Callback` which will send a message to the linked component's
+    /// Creates a `Callback` which will send a message to the linked component's
     /// update method when invoked.
     pub fn callback<F, IN, M>(&self, function: F) -> Callback<IN>
     where
@@ -134,8 +134,23 @@ impl<COMP: Component> Scope<COMP> {
         closure.into()
     }
 
-    /// This method creates a `Callback` which will send a batch of messages back to the linked
-    /// component's update method when called.
+    /// Creates a `Callback` from a FnOnce which will send a message to the linked
+    /// component's update method when invoked.
+    pub fn callback_once<F, IN, M>(&self, function: F) -> Callback<IN>
+    where
+        M: Into<COMP::Message>,
+        F: FnOnce(IN) -> M + 'static,
+    {
+        let scope = self.clone();
+        let closure = move |input| {
+            let output = function(input);
+            scope.send_message(output);
+        };
+        Callback::once(closure)
+    }
+
+    /// Creates a `Callback` which will send a batch of messages back to the linked
+    /// component's update method when invoked.
     pub fn batch_callback<F, IN>(&self, function: F) -> Callback<IN>
     where
         F: Fn(IN) -> Vec<COMP::Message> + 'static,