diff --git a/docs/config/index.md b/docs/config/index.md
index d77d3c911219..3551904905f1 100644
--- a/docs/config/index.md
+++ b/docs/config/index.md
@@ -481,7 +481,7 @@ Silent console output from tests
 
 - **Type:** `string | string[]`
 
-Path to setup files. They will be run before each test file.
+Path to setup files. They will be run before each test file. They will be merged into [`forceRerunTriggers`](https://vitest.dev/config/#forcereruntriggers), all your tests will be rerun when setup files are changed.
 
 You can use `process.env.VITEST_POOL_ID` (integer-like string) inside to distinguish between threads (will always be `'1'`, if run with `threads: false`).
 
diff --git a/packages/vitest/src/node/config.ts b/packages/vitest/src/node/config.ts
index 882299efd112..0d7b4f24f9ec 100644
--- a/packages/vitest/src/node/config.ts
+++ b/packages/vitest/src/node/config.ts
@@ -191,6 +191,11 @@ export function resolveConfig(
     ),
   )
 
+  resolved.forceRerunTriggers = [
+    ...resolved.forceRerunTriggers,
+    ...resolved.setupFiles,
+  ]
+
   // the server has been created, we don't need to override vite.server options
   resolved.api = resolveApiConfig(options)
 
diff --git a/test/setup/package.json b/test/setup/package.json
new file mode 100644
index 000000000000..8f59d466bbb7
--- /dev/null
+++ b/test/setup/package.json
@@ -0,0 +1,11 @@
+{
+  "name": "@vitest/test-setup",
+  "private": true,
+  "scripts": {
+    "test": "vitest"
+  },
+  "devDependencies": {
+    "execa": "^6.1.0",
+    "vitest": "workspace:*"
+  }
+}
diff --git a/test/setup/setup.vitest.config.ts b/test/setup/setup.vitest.config.ts
new file mode 100644
index 000000000000..84c7a1e6f7ac
--- /dev/null
+++ b/test/setup/setup.vitest.config.ts
@@ -0,0 +1,8 @@
+import { defineConfig } from 'vitest/config'
+
+export default defineConfig({
+  test: {
+    include: ['tests/empty-setup.test.ts'],
+    setupFiles: ['setupFiles/empty-setup.ts'],
+  },
+})
diff --git a/test/setup/setupFiles/empty-setup.ts b/test/setup/setupFiles/empty-setup.ts
new file mode 100644
index 000000000000..e69de29bb2d1
diff --git a/test/setup/tests/empty-setup.test.ts b/test/setup/tests/empty-setup.test.ts
new file mode 100644
index 000000000000..2621a8919ec2
--- /dev/null
+++ b/test/setup/tests/empty-setup.test.ts
@@ -0,0 +1,5 @@
+import { expect, it } from 'vitest'
+
+it('should success', async () => {
+  expect(1 + 1).toBe(2)
+})
diff --git a/test/setup/tests/setup-files.test.ts b/test/setup/tests/setup-files.test.ts
new file mode 100644
index 000000000000..e580812e1d9e
--- /dev/null
+++ b/test/setup/tests/setup-files.test.ts
@@ -0,0 +1,25 @@
+import { promises as fs } from 'fs'
+import { afterEach, describe, expect, it } from 'vitest'
+import { execa } from 'execa'
+
+const run = async () => await execa('vitest', ['run', '--changed', '--config', 'setup.vitest.config.ts'])
+
+describe('setup files with forceRerunTrigger', () => {
+  const file = './setupFiles/empty-setup.ts'
+
+  afterEach(async () => {
+    await fs.writeFile(file, '', 'utf-8')
+  })
+
+  it('should run no tests if setup files are not changed', async () => {
+    const { stdout } = await run()
+    expect(stdout).toContain('No test files found, exiting with code 0')
+  }, 60_000)
+
+  it('should run the whole test suite if setup files are changed', async () => {
+    const codes = 'export const a = 1'
+    await fs.writeFile(file, codes, 'utf-8')
+    const { stdout } = await run()
+    expect(stdout).toContain('1 passed')
+  }, 60_000)
+})