diff --git a/src/urllib3/connectionpool.py b/src/urllib3/connectionpool.py
index d62f1f6642..db5ea8cebb 100644
--- a/src/urllib3/connectionpool.py
+++ b/src/urllib3/connectionpool.py
@@ -401,11 +401,11 @@ def _make_request(
             pass
         except Exception as e:
             print("ERROR=", e, e.args, "errno=", getattr(e, "errno", None))
-            # Python 2, Windows
+            # Python 2, Windows, macOS
             # EPIPE and ESHUTDOWN are BrokenPipeError on Python 2, and EPROTOTYPE is needed on macOS
             # https://erickt.github.io/blog/2014/11/19/adventures-in-debugging-a-potential-osx-kernel-bug/
             # Windows is ConnectionAborted which can mean that a connection hung up.
-            if e.errno not in {
+            if getattr(e, "errno", None) not in {
                 errno.EPIPE,
                 errno.ESHUTDOWN,
                 errno.EPROTOTYPE,