diff --git a/sanic/cli/app.py b/sanic/cli/app.py
index 444de0f688..3884a15d49 100644
--- a/sanic/cli/app.py
+++ b/sanic/cli/app.py
@@ -148,8 +148,17 @@ def _inspector(self):
         if unknown:
             for arg in unknown:
                 if arg.startswith("--"):
-                    key, value = arg.split("=")
-                    setattr(self.args, key.lstrip("-"), value)
+                    try:
+                        key, value = arg.split("=")
+                        key = key.lstrip("-")
+                    except ValueError:
+                        value = False if arg.startswith("--no-") else True
+                        key = (
+                            arg.replace("--no-", "")
+                            .lstrip("-")
+                            .replace("-", "_")
+                        )
+                    setattr(self.args, key, value)
 
         kwargs = {**self.args.__dict__}
         host = kwargs.pop("host")
diff --git a/sanic/cli/inspector.py b/sanic/cli/inspector.py
index 8bb8e90bf6..31aaee0948 100644
--- a/sanic/cli/inspector.py
+++ b/sanic/cli/inspector.py
@@ -47,11 +47,16 @@ def make_inspector_parser(parser: ArgumentParser) -> None:
         action=SanicSubParsersAction,
         dest="action",
         description=(
-            "Run one of the below subcommands. If you have created a custom "
-            "Inspector instance, then you can run custom commands. See ___ "
+            "Run one or none of the below subcommands. Using inspect without "
+            "a subcommand will fetch general information about the state "
+            "of the application instance.\n\n"
+            "Or, you can optionally follow inspect with a subcommand. "
+            "If you have created a custom "
+            "Inspector instance, then you can run custom commands. See "
+            "https://sanic.dev/en/guide/deployment/inspector.html"
             "for more details."
         ),
-        title="Required\n========\n  Subcommands",
+        title="  Subcommands",
         parser_class=InspectorSubParser,
     )
     reloader = subparsers.add_parser(
diff --git a/sanic/config.py b/sanic/config.py
index 0d5eabf80b..2b279482e1 100644
--- a/sanic/config.py
+++ b/sanic/config.py
@@ -126,7 +126,9 @@ class Config(dict, metaclass=DescriptorMeta):
 
     def __init__(
         self,
-        defaults: Dict[str, Union[str, bool, int, float, None]] = None,
+        defaults: Optional[
+            Dict[str, Union[str, bool, int, float, None]]
+        ] = None,
         env_prefix: Optional[str] = SANIC_PREFIX,
         keep_alive: Optional[bool] = None,
         *,
diff --git a/sanic/worker/inspector.py b/sanic/worker/inspector.py
index 487ef3c58e..c30aa6c47a 100644
--- a/sanic/worker/inspector.py
+++ b/sanic/worker/inspector.py
@@ -71,7 +71,8 @@ async def _action(self, request: Request, action: str):
             kwargs = {}
             if request.body:
                 kwargs = request.json
-            output = method(**kwargs)
+            args = kwargs.pop("args", ())
+            output = method(*args, **kwargs)
             if isawaitable(output):
                 output = await output
 
diff --git a/tests/test_cli.py b/tests/test_cli.py
index eff61a1854..cb3842e709 100644
--- a/tests/test_cli.py
+++ b/tests/test_cli.py
@@ -326,6 +326,8 @@ def test_inspector_inspect(urlopen, caplog, capsys):
         (["shutdown"], {}),
         (["scale", "9"], {"replicas": 9}),
         (["foo", "--bar=something"], {"bar": "something"}),
+        (["foo", "--bar"], {"bar": True}),
+        (["foo", "--no-bar"], {"bar": False}),
         (["foo", "positional"], {"args": ["positional"]}),
         (
             ["foo", "positional", "--bar=something"],