diff --git a/.github/workflows/wheels.yml b/.github/workflows/wheels.yml
index 04835a56..a7d13040 100644
--- a/.github/workflows/wheels.yml
+++ b/.github/workflows/wheels.yml
@@ -17,17 +17,24 @@ jobs:
       fail-fast: false
       matrix:
         os: [ "ubuntu-20.04", "macos-latest" ]
-        python: [ "pypy3.7-7.3.3","pypy3.6-7.3.3", "3.6", "3.7", "3.8", "3.9" ]
+        python: [ "pypy3.7-7.3.3", "pypy3.6-7.3.3", "3.6", "3.7", "3.8", "3.9", "3.10" ]
         platform: [ "x86_64", "i686" ]
         macos-target: [ "10.10" ]
         exclude:
           - os: "macos-latest"
             platform: "i686"
+          - os: "ubuntu-20.04"
+            python: "3.10"
         include:
           - os: "macos-latest"
             os-name: "osx"
           - os: "ubuntu-20.04"
             os-name: "focal"
+          - os: "macos-11"
+            os-name: "osx"
+            platform: "arm64"
+            python: "3.10"
+            macos-target: "11.0"
           - os: "macos-11"
             os-name: "osx"
             platform: "arm64"
@@ -70,17 +77,24 @@ jobs:
       fail-fast: false
       matrix:
         os: [ "ubuntu-20.04", "macos-latest" ]
-        python: [ "pypy3.7-7.3.3", "pypy3.6-7.3.3", "3.6", "3.7", "3.8", "3.9" ]
+        python: [ "pypy3.7-7.3.3", "pypy3.6-7.3.3", "3.6", "3.7", "3.8", "3.9", "3.10" ]
         platform: [ "x86_64", "i686" ]
         macos-target: [ "10.10" ]
         exclude:
           - os: "macos-latest"
             platform: "i686"
+          - os: "ubuntu-20.04"
+            python: "3.10"
         include:
           - os: "macos-latest"
             os-name: "osx"
           - os: "ubuntu-20.04"
             os-name: "focal"
+          - os: "macos-11"
+            os-name: "osx"
+            platform: "arm64"
+            python: "3.10"
+            macos-target: "11.0"
           - os: "macos-11"
             os-name: "osx"
             platform: "arm64"
diff --git a/config.sh b/config.sh
index 2dde6778..e87c7f8b 100644
--- a/config.sh
+++ b/config.sh
@@ -132,7 +132,7 @@ function run_tests {
         else
             python3 -m pip install numpy==1.20.3
         fi
-    else
+    elif [[ "$MB_PYTHON_VERSION" != 3.10 ]] || [[ "$PLAT" != "x86_64" ]]; then
         python3 -m pip install numpy
     fi
 
diff --git a/multibuild b/multibuild
index 84c6f7f6..13a01725 160000
--- a/multibuild
+++ b/multibuild
@@ -1 +1 @@
-Subproject commit 84c6f7f6c2b56d88197cd9d1fe928326d9c734c3
+Subproject commit 13a01725b0f0aa551ab34aa2311cdc1c77be4337