diff --git a/src/PIL/TiffImagePlugin.py b/src/PIL/TiffImagePlugin.py
index 766d46ffb23..04a63bd2b44 100644
--- a/src/PIL/TiffImagePlugin.py
+++ b/src/PIL/TiffImagePlugin.py
@@ -173,6 +173,7 @@
     (II, 1, (1,), 2, (8,), ()): ("L", "L;R"),
     (MM, 1, (1,), 2, (8,), ()): ("L", "L;R"),
     (II, 1, (1,), 1, (12,), ()): ("I;16", "I;12"),
+    (II, 0, (1,), 1, (16,), ()): ("I;16", "I;16"),
     (II, 1, (1,), 1, (16,), ()): ("I;16", "I;16"),
     (MM, 1, (1,), 1, (16,), ()): ("I;16B", "I;16B"),
     (II, 1, (1,), 2, (16,), ()): ("I;16", "I;16R"),