diff --git a/Tests/test_file_png.py b/Tests/test_file_png.py
index 9a5577bbac0..0869cc58bc5 100644
--- a/Tests/test_file_png.py
+++ b/Tests/test_file_png.py
@@ -13,7 +13,6 @@
     assert_image_equal,
     assert_image_equal_tofile,
     hopper,
-    is_big_endian,
     is_win32,
     mark_if_feature_version,
     skip_unless_feature,
@@ -77,7 +76,6 @@ def get_chunks(self, filename):
                     png.crc(cid, s)
         return chunks
 
-    @pytest.mark.xfail(is_big_endian(), reason="Fails on big-endian")
     def test_sanity(self, tmp_path):
 
         # internal version number
diff --git a/src/libImaging/Convert.c b/src/libImaging/Convert.c
index 9012cfcd74b..f4e970f51ba 100644
--- a/src/libImaging/Convert.c
+++ b/src/libImaging/Convert.c
@@ -963,10 +963,17 @@ static struct {
 
     {"HSV", "RGB", hsv2rgb},
 
+#ifdef WORDS_BIGENDIAN
+    {"I", "I;16", I_I16B},
+    {"I;16", "I", I16B_I},
+    {"L", "I;16", L_I16B},
+    {"I;16", "L", I16B_L},
+#else
     {"I", "I;16", I_I16L},
     {"I;16", "I", I16L_I},
     {"L", "I;16", L_I16L},
     {"I;16", "L", I16L_L},
+#endif
 
     {"I", "I;16L", I_I16L},
     {"I;16L", "I", I16L_I},
diff --git a/src/libImaging/GetBBox.c b/src/libImaging/GetBBox.c
index e73153600d0..b6c9adecb8b 100644
--- a/src/libImaging/GetBBox.c
+++ b/src/libImaging/GetBBox.c
@@ -181,21 +181,11 @@ ImagingGetExtrema(Imaging im, void *extrema) {
         case IMAGING_TYPE_SPECIAL:
             if (strcmp(im->mode, "I;16") == 0) {
                 UINT16 v;
-                UINT8 *pixel = *im->image8;
-#ifdef WORDS_BIGENDIAN
-                v = pixel[0] + (pixel[1] << 8);
-#else
-                memcpy(&v, pixel, sizeof(v));
-#endif
+                memcpy(&v, *im->image8, sizeof(v));
                 imin = imax = v;
                 for (y = 0; y < im->ysize; y++) {
                     for (x = 0; x < im->xsize; x++) {
-                        pixel = (UINT8 *)im->image[y] + x * sizeof(v);
-#ifdef WORDS_BIGENDIAN
-                        v = pixel[0] + (pixel[1] << 8);
-#else
-                        memcpy(&v, pixel, sizeof(v));
-#endif
+                        memcpy(&v, im->image[y] + x * sizeof(v), sizeof(v));
                         if (imin > v) {
                             imin = v;
                         } else if (imax < v) {