diff --git a/Tests/test_file_libtiff.py b/Tests/test_file_libtiff.py
index 7a5a5b46288..d6f4900cdce 100644
--- a/Tests/test_file_libtiff.py
+++ b/Tests/test_file_libtiff.py
@@ -471,6 +471,14 @@ def test_tiff_jpeg_compression(self, tmp_path):
         with Image.open(out) as reloaded:
             assert reloaded.info["compression"] == "jpeg"
 
+    def test_tiff_deflate_compression(self, tmp_path):
+        im = hopper("RGB")
+        out = str(tmp_path / "temp.tif")
+        im.save(out, compression="tiff_deflate")
+
+        with Image.open(out) as reloaded:
+            assert reloaded.info["compression"] == "tiff_adobe_deflate"
+
     def test_quality(self, tmp_path):
         im = hopper("RGB")
         out = str(tmp_path / "temp.tif")
diff --git a/src/PIL/TiffImagePlugin.py b/src/PIL/TiffImagePlugin.py
index 98c70d7c451..19bcf4419b7 100644
--- a/src/PIL/TiffImagePlugin.py
+++ b/src/PIL/TiffImagePlugin.py
@@ -1442,6 +1442,8 @@ def _save(im, fp, filename):
     elif compression == "tiff_jpeg":
         # OJPEG is obsolete, so use new-style JPEG compression instead
         compression = "jpeg"
+    elif compression == "tiff_deflate":
+        compression = "tiff_adobe_deflate"
 
     libtiff = WRITE_LIBTIFF or compression != "raw"