diff --git a/.cirrus.yml b/.cirrus.yml
index 1c2e9a6a83..5304a3d895 100644
--- a/.cirrus.yml
+++ b/.cirrus.yml
@@ -15,7 +15,7 @@ task:
     image: freebsd-11-4-release-amd64
   setup_script:
     - fetch https://sh.rustup.rs -o rustup.sh
-    - sh rustup.sh -y --profile=minimal --default-toolchain 1.41.0
+    - sh rustup.sh -y --profile=minimal --default-toolchain 1.46.0
     - $HOME/.cargo/bin/rustup target add i686-unknown-freebsd
   amd64_test_script:
     - . $HOME/.cargo/env
@@ -46,7 +46,7 @@ task:
     image: catalina-xcode
   setup_script:
     - curl --proto '=https' --tlsv1.2 -sSf -o rustup.sh https://sh.rustup.rs
-    - sh rustup.sh -y --profile=minimal --default-toolchain 1.41.0
+    - sh rustup.sh -y --profile=minimal --default-toolchain 1.46.0
     - . $HOME/.cargo/env
     - bash ci/install.sh
   script:
@@ -101,7 +101,7 @@ task:
   setup_script:
     - mkdir /tmp/home
     - curl --proto '=https' --tlsv1.2 -sSf -o rustup.sh https://sh.rustup.rs
-    - sh rustup.sh -y --profile=minimal --default-toolchain 1.41.0
+    - sh rustup.sh -y --profile=minimal --default-toolchain 1.46.0
     - . $HOME/.cargo/env
     - bash ci/install.sh
   script:
@@ -119,13 +119,13 @@ task:
     - name: Linux x86_64
       env:
         TARGET: x86_64-unknown-linux-gnu
-        TOOLCHAIN: 1.41.0
+        TOOLCHAIN: 1.46.0
     - name: Linux x86_64 musl
       env:
         TARGET: x86_64-unknown-linux-musl
-        TOOLCHAIN: 1.41.0
+        TOOLCHAIN: 1.46.0
   container:
-    image: rust:1.41
+    image: rust:1.46
   setup_script:
     - rustup toolchain install $TOOLCHAIN
     - rustup target add --toolchain $TOOLCHAIN $TARGET
@@ -173,7 +173,7 @@ task:
       env:
         TARGET: x86_64-fuchsia
   container:
-    image: rust:1.41
+    image: rust:1.46
   setup_script:
     - rustup target add $TARGET
   script:
diff --git a/CHANGELOG.md b/CHANGELOG.md
index 3e2c968089..c2037cb58a 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -50,6 +50,9 @@ This project adheres to [Semantic Versioning](https://semver.org/).
   where it previously would've had undefined behavior.
   (#[1484](https://github.com/nix-rust/nix/pull/1484))
 
+- Minimum supported Rust version is now 1.46.0.
+  ([#1492](https://github.com/nix-rust/nix/pull/1492))
+
 ### Fixed
 
 - Added more errno definitions for better backwards compatibility with
diff --git a/Cargo.toml b/Cargo.toml
index dc565aee0e..9e48fc0ccd 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -26,7 +26,7 @@ targets = [
 
 [dependencies]
 libc = { git = "https://github.com/rust-lang/libc", rev = "f5e31f208", features = [ "extra_traits" ] }
-bitflags = "1.1"
+bitflags = "1.3.1"
 cfg-if = "1.0"
 
 [target.'cfg(not(target_os = "redox"))'.dependencies]
diff --git a/README.md b/README.md
index 895ef1ee87..52ac53f4e0 100644
--- a/README.md
+++ b/README.md
@@ -87,7 +87,7 @@ Tier 3:
 
 ## Usage
 
-`nix` requires Rust 1.41.0 or newer.
+`nix` requires Rust 1.46.0 or newer.
 
 To use `nix`, add this to your `Cargo.toml`: