diff --git a/src/mongo_client.ts b/src/mongo_client.ts
index 45f8a240f98..5b870fae576 100644
--- a/src/mongo_client.ts
+++ b/src/mongo_client.ts
@@ -21,6 +21,7 @@ import { PromiseProvider } from './promise_provider';
 import type { ReadConcern, ReadConcernLevel, ReadConcernLike } from './read_concern';
 import { ReadPreference, ReadPreferenceMode } from './read_preference';
 import type { TagSet } from './sdam/server_description';
+import { readPreferenceServerSelector } from './sdam/server_selection';
 import type { SrvPoller } from './sdam/srv_polling';
 import type { Topology, TopologyEvents } from './sdam/topology';
 import { ClientSession, ClientSessionOptions, ServerSessionPool } from './sessions';
@@ -500,6 +501,17 @@ export class MongoClient extends TypedEventEmitter<MongoClientEvents> {
 
       Promise.all(activeSessionEnds)
         .then(() => {
+          // If we would attempt to select a server and get nothing back when using a direct
+          // connection (which is always topology type single and cannot transition to unknown)
+          // we short circuit.
+          const selector = readPreferenceServerSelector(ReadPreference.primaryPreferred);
+          const topologyDescription = this.topology.description;
+          const serverDescriptions = Array.from(topologyDescription.servers.values());
+          const servers = selector(topologyDescription, serverDescriptions);
+          if (servers.length === 0) {
+            return callback();
+          }
+
           const endSessions = Array.from(this.s.sessionPool.sessions, ({ id }) => id);
           if (endSessions.length === 0) return;
           return this.db('admin')
diff --git a/test/integration/node-specific/mongo_client.test.ts b/test/integration/node-specific/mongo_client.test.ts
index f459ae36152..6081af99c68 100644
--- a/test/integration/node-specific/mongo_client.test.ts
+++ b/test/integration/node-specific/mongo_client.test.ts
@@ -13,6 +13,7 @@ import {
 } from '../../../src';
 import { Connection } from '../../../src/cmap/connection';
 import { Db } from '../../../src/db';
+import { ServerDescription } from '../../../src/sdam/server_description';
 import { Topology } from '../../../src/sdam/topology';
 import { getTopology, isHello } from '../../../src/utils';
 import { runLater } from '../../tools/utils';
@@ -649,5 +650,25 @@ describe('class MongoClient', function () {
       expect(endEvents).to.have.lengthOf(1);
       expect(endEvents[0]).to.have.property('reply', undefined); // noReponse: true
     });
+
+    context('when server selection would return no servers', () => {
+      const serverDescription = new ServerDescription('a:1');
+
+      it('short circuits and does not end sessions', async () => {
+        const session = client.startSession(); // make a session to be ended
+        await client.db('test').command({ ping: 1 }, { session });
+        await session.endSession();
+
+        const startedEvents: CommandStartedEvent[] = [];
+        client.on('commandStarted', event => startedEvents.push(event));
+
+        const servers = new Map<string, ServerDescription>();
+        servers.set(serverDescription.address, serverDescription);
+        client.topology.description.servers = servers;
+        await client.close();
+
+        expect(startedEvents).to.be.empty;
+      });
+    });
   });
 });