diff --git a/src/compiler/checker.ts b/src/compiler/checker.ts
index 07996e0bcdd41..9e61193a1f962 100644
--- a/src/compiler/checker.ts
+++ b/src/compiler/checker.ts
@@ -1091,6 +1091,16 @@ namespace ts {
             }
         }
         function errorOrSuggestion(isError: boolean, location: Node, message: DiagnosticMessage | DiagnosticMessageChain, arg0?: string | number, arg1?: string | number, arg2?: string | number, arg3?: string | number): void {
+             // Pseudo-synthesized input node
+            if (location.pos < 0 || location.end < 0) {
+                if (!isError) {
+                    return; // Drop suggestions (we have no span to suggest on)
+                }
+                // Issue errors globally
+                const file = getSourceFileOfNode(location);
+                addErrorOrSuggestion(isError, "message" in message ? createFileDiagnostic(file, 0, 0, message, arg0, arg1, arg2, arg3) : createDiagnosticForFileFromMessageChain(file, message)); // eslint-disable-line no-in-operator
+                return;
+            }
             addErrorOrSuggestion(isError, "message" in message ? createDiagnosticForNode(location, message, arg0, arg1, arg2, arg3) : createDiagnosticForNodeFromMessageChain(location, message)); // eslint-disable-line no-in-operator
         }
 
diff --git a/src/compiler/utilities.ts b/src/compiler/utilities.ts
index 2dc1fb0475d34..295671b70449b 100644
--- a/src/compiler/utilities.ts
+++ b/src/compiler/utilities.ts
@@ -989,6 +989,18 @@ namespace ts {
         };
     }
 
+    export function createDiagnosticForFileFromMessageChain(sourceFile: SourceFile, messageChain: DiagnosticMessageChain, relatedInformation?: DiagnosticRelatedInformation[]): DiagnosticWithLocation {
+        return {
+            file: sourceFile,
+            start: 0,
+            length: 0,
+            code: messageChain.code,
+            category: messageChain.category,
+            messageText: messageChain.next ? messageChain : messageChain.messageText,
+            relatedInformation
+        };
+    }
+
     export function createDiagnosticForRange(sourceFile: SourceFile, range: TextRange, message: DiagnosticMessage): DiagnosticWithLocation {
         return {
             file: sourceFile,
diff --git a/src/testRunner/unittests/tsc/incremental.ts b/src/testRunner/unittests/tsc/incremental.ts
index fd42ccddf1843..36ea38edd0155 100644
--- a/src/testRunner/unittests/tsc/incremental.ts
+++ b/src/testRunner/unittests/tsc/incremental.ts
@@ -235,5 +235,42 @@ const a: string = 10;`, "utf-8"),
                 }
             }
         });
+
+        const jsxLibraryContent = `
+export {};
+declare global {
+    namespace JSX {
+        interface Element {}
+        interface IntrinsicElements {
+            div: {
+                propA?: boolean;
+            };
+        }
+    }
+}`;
+
+        verifyTsc({
+            scenario: "react-jsx-emit-mode",
+            subScenario: "with no backing types found doesn't crash",
+            fs: () => loadProjectFromFiles({
+                "/src/project/node_modules/react/jsx-runtime.js": "export {}", // js needs to be present so there's a resolution result
+                "/src/project/node_modules/@types/react/index.d.ts": jsxLibraryContent, // doesn't contain a jsx-runtime definition
+                "/src/project/src/index.tsx": `export const App = () => <div propA={true}></div>;`,
+                "/src/project/tsconfig.json": JSON.stringify({ compilerOptions: { module: "commonjs", jsx: "react-jsx", incremental: true, jsxImportSource: "react" } })
+            }),
+            commandLineArgs: ["--p", "src/project"]
+        });
+
+        verifyTsc({
+            scenario: "react-jsx-emit-mode",
+            subScenario: "with no backing types found doesn't crash under --strict",
+            fs: () => loadProjectFromFiles({
+                "/src/project/node_modules/react/jsx-runtime.js": "export {}", // js needs to be present so there's a resolution result
+                "/src/project/node_modules/@types/react/index.d.ts": jsxLibraryContent, // doesn't contain a jsx-runtime definition
+                "/src/project/src/index.tsx": `export const App = () => <div propA={true}></div>;`,
+                "/src/project/tsconfig.json": JSON.stringify({ compilerOptions: { module: "commonjs", jsx: "react-jsx", incremental: true, jsxImportSource: "react" } })
+            }),
+            commandLineArgs: ["--p", "src/project", "--strict"]
+        });
     });
 }
diff --git a/tests/baselines/reference/tsc/react-jsx-emit-mode/initial-build/with-no-backing-types-found-doesn't-crash-under---strict.js b/tests/baselines/reference/tsc/react-jsx-emit-mode/initial-build/with-no-backing-types-found-doesn't-crash-under---strict.js
new file mode 100644
index 0000000000000..b0b8497aaf4eb
--- /dev/null
+++ b/tests/baselines/reference/tsc/react-jsx-emit-mode/initial-build/with-no-backing-types-found-doesn't-crash-under---strict.js
@@ -0,0 +1,115 @@
+Input::
+//// [/lib/lib.d.ts]
+/// <reference no-default-lib="true"/>
+interface Boolean {}
+interface Function {}
+interface CallableFunction {}
+interface NewableFunction {}
+interface IArguments {}
+interface Number { toExponential: any; }
+interface Object {}
+interface RegExp {}
+interface String { charAt: any; }
+interface Array<T> { length: number; [n: number]: T; }
+interface ReadonlyArray<T> {}
+declare const console: { log(msg: any): void; };
+
+//// [/src/project/node_modules/@types/react/index.d.ts]
+
+export {};
+declare global {
+    namespace JSX {
+        interface Element {}
+        interface IntrinsicElements {
+            div: {
+                propA?: boolean;
+            };
+        }
+    }
+}
+
+//// [/src/project/node_modules/react/jsx-runtime.js]
+
+
+//// [/src/project/src/index.tsx]
+export const App = () => <div propA={true}></div>;
+
+//// [/src/project/tsconfig.json]
+{"compilerOptions":{"module":"commonjs","jsx":"react-jsx","incremental":true,"jsxImportSource":"react"}}
+
+
+
+Output::
+/lib/tsc --p src/project --strict
+src/project/src/index.tsx:1:26 - error TS7016: Could not find a declaration file for module 'react/jsx-runtime'. '/src/project/node_modules/react/jsx-runtime.js' implicitly has an 'any' type.
+
+1 export const App = () => <div propA={true}></div>;
+                           ~~~~~~~~~~~~~~~~~~~~~~~~
+
+
+Found 1 error.
+
+exitCode:: ExitStatus.DiagnosticsPresent_OutputsGenerated
+
+
+//// [/src/project/src/index.js]
+"use strict";
+exports.__esModule = true;
+exports.App = void 0;
+var jsx_runtime_1 = require("react/jsx-runtime");
+var App = function () { return jsx_runtime_1.jsx("div", { propA: true }, void 0); };
+exports.App = App;
+
+
+//// [/src/project/tsconfig.tsbuildinfo]
+{
+  "program": {
+    "fileInfos": {
+      "../../lib/lib.d.ts": {
+        "version": "3858781397-/// <reference no-default-lib=\"true\"/>\ninterface Boolean {}\ninterface Function {}\ninterface CallableFunction {}\ninterface NewableFunction {}\ninterface IArguments {}\ninterface Number { toExponential: any; }\ninterface Object {}\ninterface RegExp {}\ninterface String { charAt: any; }\ninterface Array<T> { length: number; [n: number]: T; }\ninterface ReadonlyArray<T> {}\ndeclare const console: { log(msg: any): void; };",
+        "signature": "3858781397-/// <reference no-default-lib=\"true\"/>\ninterface Boolean {}\ninterface Function {}\ninterface CallableFunction {}\ninterface NewableFunction {}\ninterface IArguments {}\ninterface Number { toExponential: any; }\ninterface Object {}\ninterface RegExp {}\ninterface String { charAt: any; }\ninterface Array<T> { length: number; [n: number]: T; }\ninterface ReadonlyArray<T> {}\ndeclare const console: { log(msg: any): void; };",
+        "affectsGlobalScope": true
+      },
+      "./src/index.tsx": {
+        "version": "-14760199789-export const App = () => <div propA={true}></div>;",
+        "signature": "-8716173275-/// <reference types=\"react\" />\r\nexport declare const App: () => JSX.Element;\r\n",
+        "affectsGlobalScope": false
+      },
+      "./node_modules/@types/react/index.d.ts": {
+        "version": "-16587767667-\nexport {};\ndeclare global {\n    namespace JSX {\n        interface Element {}\n        interface IntrinsicElements {\n            div: {\n                propA?: boolean;\n            };\n        }\n    }\n}",
+        "signature": "-16587767667-\nexport {};\ndeclare global {\n    namespace JSX {\n        interface Element {}\n        interface IntrinsicElements {\n            div: {\n                propA?: boolean;\n            };\n        }\n    }\n}",
+        "affectsGlobalScope": true
+      }
+    },
+    "options": {
+      "module": 1,
+      "jsx": 4,
+      "incremental": true,
+      "jsxImportSource": "react",
+      "project": "./",
+      "strict": true,
+      "configFilePath": "./tsconfig.json"
+    },
+    "referencedMap": {},
+    "exportedModulesMap": {},
+    "semanticDiagnosticsPerFile": [
+      "../../lib/lib.d.ts",
+      "./node_modules/@types/react/index.d.ts",
+      [
+        "./src/index.tsx",
+        [
+          {
+            "file": "./src/index.tsx",
+            "start": 25,
+            "length": 24,
+            "code": 7016,
+            "category": 1,
+            "messageText": "Could not find a declaration file for module 'react/jsx-runtime'. '/src/project/node_modules/react/jsx-runtime.js' implicitly has an 'any' type."
+          }
+        ]
+      ]
+    ]
+  },
+  "version": "FakeTSVersion"
+}
+
diff --git a/tests/baselines/reference/tsc/react-jsx-emit-mode/initial-build/with-no-backing-types-found-doesn't-crash.js b/tests/baselines/reference/tsc/react-jsx-emit-mode/initial-build/with-no-backing-types-found-doesn't-crash.js
new file mode 100644
index 0000000000000..da35f20174d3c
--- /dev/null
+++ b/tests/baselines/reference/tsc/react-jsx-emit-mode/initial-build/with-no-backing-types-found-doesn't-crash.js
@@ -0,0 +1,94 @@
+Input::
+//// [/lib/lib.d.ts]
+/// <reference no-default-lib="true"/>
+interface Boolean {}
+interface Function {}
+interface CallableFunction {}
+interface NewableFunction {}
+interface IArguments {}
+interface Number { toExponential: any; }
+interface Object {}
+interface RegExp {}
+interface String { charAt: any; }
+interface Array<T> { length: number; [n: number]: T; }
+interface ReadonlyArray<T> {}
+declare const console: { log(msg: any): void; };
+
+//// [/src/project/node_modules/@types/react/index.d.ts]
+
+export {};
+declare global {
+    namespace JSX {
+        interface Element {}
+        interface IntrinsicElements {
+            div: {
+                propA?: boolean;
+            };
+        }
+    }
+}
+
+//// [/src/project/node_modules/react/jsx-runtime.js]
+
+
+//// [/src/project/src/index.tsx]
+export const App = () => <div propA={true}></div>;
+
+//// [/src/project/tsconfig.json]
+{"compilerOptions":{"module":"commonjs","jsx":"react-jsx","incremental":true,"jsxImportSource":"react"}}
+
+
+
+Output::
+/lib/tsc --p src/project
+exitCode:: ExitStatus.Success
+
+
+//// [/src/project/src/index.js]
+"use strict";
+exports.__esModule = true;
+exports.App = void 0;
+var jsx_runtime_1 = require("react/jsx-runtime");
+var App = function () { return jsx_runtime_1.jsx("div", { propA: true }, void 0); };
+exports.App = App;
+
+
+//// [/src/project/tsconfig.tsbuildinfo]
+{
+  "program": {
+    "fileInfos": {
+      "../../lib/lib.d.ts": {
+        "version": "3858781397-/// <reference no-default-lib=\"true\"/>\ninterface Boolean {}\ninterface Function {}\ninterface CallableFunction {}\ninterface NewableFunction {}\ninterface IArguments {}\ninterface Number { toExponential: any; }\ninterface Object {}\ninterface RegExp {}\ninterface String { charAt: any; }\ninterface Array<T> { length: number; [n: number]: T; }\ninterface ReadonlyArray<T> {}\ndeclare const console: { log(msg: any): void; };",
+        "signature": "3858781397-/// <reference no-default-lib=\"true\"/>\ninterface Boolean {}\ninterface Function {}\ninterface CallableFunction {}\ninterface NewableFunction {}\ninterface IArguments {}\ninterface Number { toExponential: any; }\ninterface Object {}\ninterface RegExp {}\ninterface String { charAt: any; }\ninterface Array<T> { length: number; [n: number]: T; }\ninterface ReadonlyArray<T> {}\ndeclare const console: { log(msg: any): void; };",
+        "affectsGlobalScope": true
+      },
+      "./src/index.tsx": {
+        "version": "-14760199789-export const App = () => <div propA={true}></div>;",
+        "signature": "-8716173275-/// <reference types=\"react\" />\r\nexport declare const App: () => JSX.Element;\r\n",
+        "affectsGlobalScope": false
+      },
+      "./node_modules/@types/react/index.d.ts": {
+        "version": "-16587767667-\nexport {};\ndeclare global {\n    namespace JSX {\n        interface Element {}\n        interface IntrinsicElements {\n            div: {\n                propA?: boolean;\n            };\n        }\n    }\n}",
+        "signature": "-16587767667-\nexport {};\ndeclare global {\n    namespace JSX {\n        interface Element {}\n        interface IntrinsicElements {\n            div: {\n                propA?: boolean;\n            };\n        }\n    }\n}",
+        "affectsGlobalScope": true
+      }
+    },
+    "options": {
+      "module": 1,
+      "jsx": 4,
+      "incremental": true,
+      "jsxImportSource": "react",
+      "project": "./",
+      "configFilePath": "./tsconfig.json"
+    },
+    "referencedMap": {},
+    "exportedModulesMap": {},
+    "semanticDiagnosticsPerFile": [
+      "../../lib/lib.d.ts",
+      "./node_modules/@types/react/index.d.ts",
+      "./src/index.tsx"
+    ]
+  },
+  "version": "FakeTSVersion"
+}
+