diff --git a/lodash.js b/lodash.js
index cbf3b38487..71353bf7bf 100644
--- a/lodash.js
+++ b/lodash.js
@@ -3990,6 +3990,10 @@
         var key = toKey(path[index]),
             newValue = value;
 
+        if (key === '__proto__' || key === 'constructor' || key === 'prototype') {
+          return object;
+        }
+
         if (index != lastIndex) {
           var objValue = nested[key];
           newValue = customizer ? customizer(objValue, key, nested) : undefined;
diff --git a/test/test.js b/test/test.js
index 2bfb54669d..50c3d347ec 100644
--- a/test/test.js
+++ b/test/test.js
@@ -25787,6 +25787,39 @@
     });
   });
 
+  // zipObjectDeep prototype pollution
+  ['__proto__', 'constructor', 'prototype'].forEach(function (keyToTest) {
+    QUnit.test('zipObjectDeep is not setting ' + keyToTest + ' on global', function (assert) {
+      assert.expect(1);
+
+      _.zipObjectDeep([keyToTest + '.a'], ['newValue']);
+      // Can't access plain `a` as it's not defined and test fails
+      assert.notEqual(root['a'], 'newValue');
+    });
+
+    QUnit.test('zipObjectDeep is not overwriting ' + keyToTest + ' on vars', function (assert) {
+      assert.expect(3);
+
+      const b = 'oldValue'
+      _.zipObjectDeep([keyToTest + '.b'], ['newValue']);
+      assert.equal(b, 'oldValue');
+      assert.notEqual(root['b'], 'newValue');
+
+      // ensure nothing was created
+      assert.notOk(root['b']);
+    });
+
+    QUnit.test('zipObjectDeep is not overwriting global.' + keyToTest, function (assert) {
+      assert.expect(2);
+
+      _.zipObjectDeep([root + '.' + keyToTest + '.c'], ['newValue']);
+      assert.notEqual(root['c'], 'newValue');
+
+      // ensure nothing was created
+      assert.notOk(root['c']);
+    });
+  });
+
   /*--------------------------------------------------------------------------*/
 
   QUnit.module('lodash.zipWith');