diff --git a/psalm-baseline.xml b/psalm-baseline.xml
index 47be887f..ce464c80 100644
--- a/psalm-baseline.xml
+++ b/psalm-baseline.xml
@@ -243,9 +243,8 @@
   </file>
   <file src="src/ServerRequestFactory.php">
     <LessSpecificReturnStatement occurrences="1"/>
-    <MixedArgument occurrences="2">
+    <MixedArgument occurrences="1">
       <code>$headers['cookie']</code>
-      <code>$host</code>
     </MixedArgument>
     <MixedArgumentTypeCoercion occurrences="1">
       <code>$headers</code>
diff --git a/src/ServerRequestFactory.php b/src/ServerRequestFactory.php
index 30eb71cb..506970d9 100644
--- a/src/ServerRequestFactory.php
+++ b/src/ServerRequestFactory.php
@@ -168,7 +168,15 @@ private static function marshalHostAndPort(array $server, array $headers) : arra
 
         $host = self::getHeaderFromArray('host', $headers, false);
         if ($host !== false) {
-            return self::marshalHostAndPortFromHeader($host);
+            // Ignore obviously malformed host headers:
+            // - Whitespace is invalid within a hostname and break the URI representation within HTTP.
+            //   non-printable characters other than SPACE and TAB are already rejected by HeaderSecurity.
+            // - A comma indicates that multiple host headers have been sent which is not legal
+            //   and might be used in an attack where a load balancer sees a different host header
+            //   than Diactoros.
+            if (! \preg_match('/[\\t ,]/', $host)) {
+                return self::marshalHostAndPortFromHeader($host);
+            }
         }
 
         if (! isset($server['SERVER_NAME'])) {
@@ -289,9 +297,10 @@ private static function marshalHostAndPortFromHeader($host): array
     /**
      * Retrieve a header value from an array of headers using a case-insensitive lookup.
      *
+     * @template T
      * @param array<string, string|list<string>> $headers Key/value header pairs
-     * @param mixed $default Default value to return if header not found
-     * @return mixed
+     * @param T $default Default value to return if header not found
+     * @return string|T
      */
     private static function getHeaderFromArray(string $name, array $headers, $default = null)
     {
diff --git a/test/ServerRequestFactoryTest.php b/test/ServerRequestFactoryTest.php
index eeda1682..e52c0aad 100644
--- a/test/ServerRequestFactoryTest.php
+++ b/test/ServerRequestFactoryTest.php
@@ -786,4 +786,40 @@ public function testHonorsHostHeaderOverServerNameWhenMarshalingUrl(): void
         $uri = $request->getUri();
         $this->assertSame('example.com', $uri->getHost());
     }
+
+    /**
+     * @psalm-return iterable<string, array{
+     *     0: string
+     * }>
+     */
+    public function invalidHostHeaders(): iterable
+    {
+        return [
+            'comma' => ['example.com,example.net'],
+            'space' => ['example com'],
+            'tab' => ["example\tcom"],
+        ];
+    }
+
+    /**
+     * @dataProvider invalidHostHeaders
+     */
+    public function testRejectsDuplicatedHostHeader(string $host): void
+    {
+        $server = [
+            'HTTP_HOST' => $host,
+        ];
+
+        $request = ServerRequestFactory::fromGlobals(
+            $server,
+            null,
+            null,
+            null,
+            null,
+            new DoNotFilter()
+        );
+
+        $uri = $request->getUri();
+        $this->assertSame('', $uri->getHost());
+    }
 }