diff --git a/.gitignore b/.gitignore
index 6a9f8063929462..44abdd7bf563db 100644
--- a/.gitignore
+++ b/.gitignore
@@ -1,5 +1,6 @@
 .DS_Store
 node_modules
+!**/glob-import/dir/node_modules
 dist
 dist-ssr
 TODOs.md
diff --git a/packages/playground/glob-import/__tests__/glob-import.spec.ts b/packages/playground/glob-import/__tests__/glob-import.spec.ts
index 311f94cd00571a..3a2425736548ea 100644
--- a/packages/playground/glob-import/__tests__/glob-import.spec.ts
+++ b/packages/playground/glob-import/__tests__/glob-import.spec.ts
@@ -45,6 +45,10 @@ const allResult = {
   }
 }
 
+const nodeModulesResult = {
+  '/dir/node_modules/hoge.js': { msg: 'hoge' }
+}
+
 const rawResult = {
   '/dir/baz.json': {
     msg: 'baz'
@@ -55,6 +59,9 @@ test('should work', async () => {
   expect(await page.textContent('.result')).toBe(
     JSON.stringify(allResult, null, 2)
   )
+  expect(await page.textContent('.result-node_modules')).toBe(
+    JSON.stringify(nodeModulesResult, null, 2)
+  )
 })
 
 test('import glob raw', async () => {
diff --git a/packages/playground/glob-import/dir/node_modules/hoge.js b/packages/playground/glob-import/dir/node_modules/hoge.js
new file mode 100644
index 00000000000000..874eb4312f0dc5
--- /dev/null
+++ b/packages/playground/glob-import/dir/node_modules/hoge.js
@@ -0,0 +1 @@
+export const msg = 'hoge'
diff --git a/packages/playground/glob-import/index.html b/packages/playground/glob-import/index.html
index e408ec8adda602..bb5e2f3c18f752 100644
--- a/packages/playground/glob-import/index.html
+++ b/packages/playground/glob-import/index.html
@@ -1,8 +1,30 @@
 <pre class="result"></pre>
+<pre class="result-node_modules"></pre>
 <pre class="globraw"></pre>
 
 <script type="module" src="./dir/index.js"></script>
 <script type="module">
+  function useImports(modules, selector) {
+    for (const path in modules) {
+      modules[path]().then((mod) => {
+        console.log(path, mod)
+      })
+    }
+
+    const keys = Object.keys(modules)
+    Promise.all(keys.map((key) => modules[key]())).then((mods) => {
+      const res = {}
+      mods.forEach((m, i) => {
+        res[keys[i]] = m
+      })
+      document.querySelector(selector).textContent = JSON.stringify(
+        res,
+        null,
+        2
+      )
+    })
+  }
+
   const modules = import.meta.glob(
     '/dir/**'
     // for test: annotation contain ")"
@@ -10,21 +32,10 @@
      * for test: annotation contain ")"
      * */
   )
+  useImports(modules, '.result')
 
-  for (const path in modules) {
-    modules[path]().then((mod) => {
-      console.log(path, mod)
-    })
-  }
-
-  const keys = Object.keys(modules)
-  Promise.all(keys.map((key) => modules[key]())).then((mods) => {
-    const res = {}
-    mods.forEach((m, i) => {
-      res[keys[i]] = m
-    })
-    document.querySelector('.result').textContent = JSON.stringify(res, null, 2)
-  })
+  const nodeModules = import.meta.glob('/dir/node_modules/**')
+  useImports(nodeModules, '.result-node_modules')
 </script>
 
 <script type="module">
diff --git a/packages/vite/src/node/importGlob.ts b/packages/vite/src/node/importGlob.ts
index 0a5a0faeccbab1..66f0a35b892c2d 100644
--- a/packages/vite/src/node/importGlob.ts
+++ b/packages/vite/src/node/importGlob.ts
@@ -69,7 +69,8 @@ export async function transformImportGlob(
   }
   const files = glob.sync(pattern, {
     cwd: base,
-    ignore: ['**/node_modules/**']
+    // Ignore node_modules by default unless explicitly indicated in the pattern
+    ignore: /(^|\/)node_modules\//.test(pattern) ? [] : ['**/node_modules/**']
   })
   const imports: string[] = []
   let importsString = ``