index.rst

Welcome

Welcome to Silicos-it!

Silicos-it has extensive chemoinformatics expertise to help you solve various questions in these domains:

   ✓  hit identification  [ docking and pharmacophore modeling ]
   ✓  high-throughput screening  [ outlier detection and post-data analysis ]
   ✓  compound libraries  [ characterisation, clustering, selection and acquisition ]
   ✓  chemistry-aware custom-made IT-applications  [ development and integration ]

Open source and sharing

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Silicos-it contributes its expertise to the chemoinformatics community by porting its source code into the open source domain. Famous examples include our spectrophore descriptors, the filtering program |filter-it| and the pharmacophore tool |align-it|. Information and downloads of all our open source programs are found in the :ref:`software <software>` section.

This site has been developed to share information on open source chemoinformatics and how it can help you in your daily work. Our :ref:`cookbook <cookbook>` groups together hints for working with molecular toolkits, shares known problems and gives insight in our learning experiences. The :ref:`molspace <molspace>` section gives you some background on our large collection of vendor compounds that we maintain to support our clients with a variety of chemoinformatics solutions. And finally, our :ref:`links <links>` page gives you access to other sites in the chemoinformatics arena that we find interesting enough for sharing.

Customers and partners

Over many years, Silicos-it has build up a very diverse and interesting customer base, including:

   ✓  pharmaceuticals  [ to identify novel inhibitors against challenging biological targets ]
   ✓  biotechnology companies  [ to find leads using docking and pharmacophore approaches ]
   ✓  startups  [ in need of molecular modeling support for their lead optimization efforts ]
   ✓  universities  [ to setup internal compound database and storage systems ]

In order to bring to our customers an even wider range of IT-support, we have also setup extensive partnerships with Altran and Emweb. We hope that this website encourages you to :ref:`contact us <about_contact>` to discuss potential collaborative work.

.. toctree::
   :hidden:
   :maxdepth: 3

   self
   software/software
   cookbook/cookbook
   molspace/molspace
   links/links
   About <about/about>