diff --git a/packages/grafana-ui/src/components/ConfirmModal/ConfirmModal.story.tsx b/packages/grafana-ui/src/components/ConfirmModal/ConfirmModal.story.tsx
index 2255b431718c..4135e314a1fa 100644
--- a/packages/grafana-ui/src/components/ConfirmModal/ConfirmModal.story.tsx
+++ b/packages/grafana-ui/src/components/ConfirmModal/ConfirmModal.story.tsx
@@ -46,6 +46,7 @@ export const Basic: ComponentStory<typeof ConfirmModal> = ({
   body,
   description,
   confirmText,
+  confirmButtonVariant,
   dismissText,
   icon,
   isOpen,
@@ -58,6 +59,7 @@ export const Basic: ComponentStory<typeof ConfirmModal> = ({
       body={body}
       description={description}
       confirmText={confirmText}
+      confirmButtonVariant={confirmButtonVariant}
       dismissText={dismissText}
       icon={icon}
       onConfirm={onConfirm}
@@ -77,6 +79,7 @@ Basic.args = {
   body: 'Are you sure you want to delete this user?',
   description: 'Removing the user will not remove any dashboards the user has created',
   confirmText: 'Delete',
+  confirmButtonVariant: 'destructive',
   dismissText: 'Cancel',
   icon: 'exclamation-triangle',
   isOpen: true,
@@ -112,7 +115,7 @@ export const AlternativeAction: ComponentStory<typeof ConfirmModal> = ({
 
 AlternativeAction.parameters = {
   controls: {
-    exclude: [...defaultExcludes, 'confirmationText'],
+    exclude: [...defaultExcludes, 'confirmationText', 'confirmButtonVariant'],
   },
 };
 
@@ -155,7 +158,7 @@ export const WithConfirmation: ComponentStory<typeof ConfirmModal> = ({
 
 WithConfirmation.parameters = {
   controls: {
-    exclude: [...defaultExcludes, 'alternativeText'],
+    exclude: [...defaultExcludes, 'alternativeText', 'confirmButtonVariant'],
   },
 };
 
diff --git a/packages/grafana-ui/src/components/ConfirmModal/ConfirmModal.tsx b/packages/grafana-ui/src/components/ConfirmModal/ConfirmModal.tsx
index 0251fbcfd0c0..86058fa945f7 100644
--- a/packages/grafana-ui/src/components/ConfirmModal/ConfirmModal.tsx
+++ b/packages/grafana-ui/src/components/ConfirmModal/ConfirmModal.tsx
@@ -7,7 +7,7 @@ import { selectors } from '@grafana/e2e-selectors';
 import { HorizontalGroup, Input } from '..';
 import { useStyles2 } from '../../themes';
 import { IconName } from '../../types/icon';
-import { Button } from '../Button';
+import { Button, ButtonVariant } from '../Button';
 import { Modal } from '../Modal/Modal';
 
 export interface ConfirmModalProps {
@@ -31,6 +31,8 @@ export interface ConfirmModalProps {
   confirmationText?: string;
   /** Text for alternative button */
   alternativeText?: string;
+  /** Confirm button variant */
+  confirmButtonVariant?: ButtonVariant;
   /** Confirm action callback */
   onConfirm(): void;
   /** Dismiss action callback */
@@ -53,6 +55,7 @@ export const ConfirmModal = ({
   onConfirm,
   onDismiss,
   onAlternative,
+  confirmButtonVariant = 'destructive',
 }: ConfirmModalProps): JSX.Element => {
   const [disabled, setDisabled] = useState(Boolean(confirmationText));
   const styles = useStyles2(getStyles);
@@ -86,7 +89,7 @@ export const ConfirmModal = ({
           {dismissText}
         </Button>
         <Button
-          variant="destructive"
+          variant={confirmButtonVariant}
           onClick={onConfirm}
           disabled={disabled}
           ref={buttonRef}
diff --git a/public/app/core/components/SharedPreferences/SharedPreferences.tsx b/public/app/core/components/SharedPreferences/SharedPreferences.tsx
index e9ab93f98674..c5cc50cc4f53 100644
--- a/public/app/core/components/SharedPreferences/SharedPreferences.tsx
+++ b/public/app/core/components/SharedPreferences/SharedPreferences.tsx
@@ -26,6 +26,7 @@ import { UserPreferencesDTO } from 'app/types';
 export interface Props {
   resourceUri: string;
   disabled?: boolean;
+  onConfirm?: () => Promise<boolean>;
 }
 
 export type State = UserPreferencesDTO;
@@ -85,9 +86,13 @@ export class SharedPreferences extends PureComponent<Props, State> {
   }
 
   onSubmitForm = async () => {
-    const { homeDashboardUID, theme, timezone, weekStart, language, queryHistory } = this.state;
-    await this.service.update({ homeDashboardUID, theme, timezone, weekStart, language, queryHistory });
-    window.location.reload();
+    const confirmationResult = this.props.onConfirm ? await this.props.onConfirm() : true;
+
+    if (confirmationResult) {
+      const { homeDashboardUID, theme, timezone, weekStart, language, queryHistory } = this.state;
+      await this.service.update({ homeDashboardUID, theme, timezone, weekStart, language, queryHistory });
+      window.location.reload();
+    }
   };
 
   onThemeChanged = (value: string) => {
diff --git a/public/app/core/services/ModalManager.ts b/public/app/core/services/ModalManager.ts
index ce7f3b02d7e2..92f59748d3fc 100644
--- a/public/app/core/services/ModalManager.ts
+++ b/public/app/core/services/ModalManager.ts
@@ -51,6 +51,7 @@ export class ModalManager {
     const {
       confirmText,
       onConfirm = () => undefined,
+      onDismiss,
       text2,
       altActionText,
       onAltAction,
@@ -60,9 +61,11 @@ export class ModalManager {
       yesText = 'Yes',
       icon,
       title = 'Confirm',
+      yesButtonVariant,
     } = payload;
     const props: ConfirmModalProps = {
       confirmText: yesText,
+      confirmButtonVariant: yesButtonVariant,
       confirmationText: confirmText,
       icon,
       title,
@@ -74,7 +77,10 @@ export class ModalManager {
         onConfirm();
         this.onReactModalDismiss();
       },
-      onDismiss: this.onReactModalDismiss,
+      onDismiss: () => {
+        onDismiss?.();
+        this.onReactModalDismiss();
+      },
       onAlternative: onAltAction
         ? () => {
             onAltAction();
diff --git a/public/app/features/org/OrgDetailsPage.test.tsx b/public/app/features/org/OrgDetailsPage.test.tsx
index e566078ba8f2..018e589d471a 100644
--- a/public/app/features/org/OrgDetailsPage.test.tsx
+++ b/public/app/features/org/OrgDetailsPage.test.tsx
@@ -1,8 +1,12 @@
-import { render } from '@testing-library/react';
+import { render, screen } from '@testing-library/react';
+import userEvent from '@testing-library/user-event';
 import React from 'react';
+import { Provider } from 'react-redux';
 import { mockToolkitActionCreator } from 'test/core/redux/mocks';
 
 import { NavModel } from '@grafana/data';
+import { ModalManager } from 'app/core/services/ModalManager';
+import { configureStore } from 'app/store/configureStore';
 
 import { backendSrv } from '../../core/services/backend_srv';
 import { Organization } from '../../types';
@@ -12,6 +16,7 @@ import { setOrganizationName } from './state/reducers';
 
 jest.mock('app/core/core', () => {
   return {
+    ...jest.requireActual('app/core/core'),
     contextSrv: {
       hasPermission: () => true,
     },
@@ -56,7 +61,11 @@ const setup = (propOverrides?: object) => {
   };
   Object.assign(props, propOverrides);
 
-  render(<OrgDetailsPage {...props} />);
+  render(
+    <Provider store={configureStore()}>
+      <OrgDetailsPage {...props} />
+    </Provider>
+  );
 };
 
 describe('Render', () => {
@@ -84,4 +93,24 @@ describe('Render', () => {
       })
     ).not.toThrow();
   });
+
+  it('should show a modal when submitting', async () => {
+    new ModalManager().init();
+    setup({
+      organization: {
+        name: 'Cool org',
+        id: 1,
+      },
+      preferences: {
+        homeDashboardUID: 'home-dashboard',
+        theme: 'Default',
+        timezone: 'Default',
+        locale: '',
+      },
+    });
+
+    await userEvent.click(screen.getByRole('button', { name: 'Save' }));
+
+    expect(screen.getByText('Confirm preferences update')).toBeInTheDocument();
+  });
 });
diff --git a/public/app/features/org/OrgDetailsPage.tsx b/public/app/features/org/OrgDetailsPage.tsx
index 57c21a83a63e..27fb009c7406 100644
--- a/public/app/features/org/OrgDetailsPage.tsx
+++ b/public/app/features/org/OrgDetailsPage.tsx
@@ -5,9 +5,10 @@ import { NavModel } from '@grafana/data';
 import { VerticalGroup } from '@grafana/ui';
 import { Page } from 'app/core/components/Page/Page';
 import SharedPreferences from 'app/core/components/SharedPreferences/SharedPreferences';
-import { contextSrv } from 'app/core/core';
+import { appEvents, contextSrv } from 'app/core/core';
 import { getNavModel } from 'app/core/selectors/navModel';
 import { AccessControlAction, Organization, StoreState } from 'app/types';
+import { ShowConfirmModalEvent } from 'app/types/events';
 
 import OrgProfile from './OrgProfile';
 import { loadOrganization, updateOrganization } from './state/actions';
@@ -31,6 +32,21 @@ export class OrgDetailsPage extends PureComponent<Props> {
     this.props.updateOrganization();
   };
 
+  handleConfirm = () => {
+    return new Promise<boolean>((resolve) => {
+      appEvents.publish(
+        new ShowConfirmModalEvent({
+          title: 'Confirm preferences update',
+          text: 'This will update the preferences for the whole organization. Are you sure you want to update the preferences?',
+          yesText: 'Save',
+          yesButtonVariant: 'primary',
+          onConfirm: async () => resolve(true),
+          onDismiss: async () => resolve(false),
+        })
+      );
+    });
+  };
+
   render() {
     const { navModel, organization } = this.props;
     const isLoading = Object.keys(organization).length === 0;
@@ -44,7 +60,9 @@ export class OrgDetailsPage extends PureComponent<Props> {
           {!isLoading && (
             <VerticalGroup spacing="lg">
               {canReadOrg && <OrgProfile onSubmit={this.onUpdateOrganization} orgName={organization.name} />}
-              {canReadPreferences && <SharedPreferences resourceUri="org" disabled={!canWritePreferences} />}
+              {canReadPreferences && (
+                <SharedPreferences resourceUri="org" disabled={!canWritePreferences} onConfirm={this.handleConfirm} />
+              )}
             </VerticalGroup>
           )}
         </Page.Contents>
diff --git a/public/app/types/events.ts b/public/app/types/events.ts
index c1a6d63c5299..8501bcc0f26b 100644
--- a/public/app/types/events.ts
+++ b/public/app/types/events.ts
@@ -1,5 +1,5 @@
 import { AnnotationQuery, BusEventBase, BusEventWithPayload, eventFactory } from '@grafana/data';
-import { IconName } from '@grafana/ui';
+import { IconName, ButtonVariant } from '@grafana/ui';
 
 /**
  * Event Payloads
@@ -37,7 +37,9 @@ export interface ShowConfirmModalPayload {
   yesText?: string;
   noText?: string;
   icon?: IconName;
+  yesButtonVariant?: ButtonVariant;
 
+  onDismiss?: () => void;
   onConfirm?: () => void;
   onAltAction?: () => void;
 }