diff --git a/structset_test.go b/structset_test.go
index 35723397..1e381b4c 100644
--- a/structset_test.go
+++ b/structset_test.go
@@ -217,3 +217,22 @@ func TestStructset_differentStructMissingField(t *testing.T) {
 		Apply(doc, NewStructset(&user, true))
 	})
 }
+
+func TestStructset_uuid(t *testing.T) {
+	// package like https://github.com/google/uuid use [16]byte to represent uuid
+	var (
+		uuid   = [16]byte{1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1}
+		record = struct {
+			UUID [16]byte `db:",primary"`
+		}{UUID: uuid}
+		doc      = NewDocument(&record)
+		mutation = Mutation{
+			Cascade: true,
+			Mutates: map[string]Mutate{
+				"uuid": Set("uuid", uuid),
+			},
+		}
+	)
+
+	assert.Equal(t, mutation, Apply(doc, NewStructset(&record, false)))
+}
diff --git a/util.go b/util.go
index c91eb583..2f1f9711 100644
--- a/util.go
+++ b/util.go
@@ -104,6 +104,11 @@ func isDeepZero(rv reflect.Value, depth int) bool {
 		c := rv.Complex()
 		return math.Float64bits(real(c)) == 0 && math.Float64bits(imag(c)) == 0
 	case reflect.Array:
+		// check one level deeper if it's an uuid ([16]byte)
+		if rv.Type().Elem().Kind() == reflect.Uint8 && rv.Len() == 16 {
+			depth += 1
+		}
+
 		for i := 0; i < rv.Len(); i++ {
 			if !isDeepZero(rv.Index(i), depth-1) {
 				return false