diff --git a/linter-requirements.txt b/linter-requirements.txt
index 744904fbc2..ec736a59c5 100644
--- a/linter-requirements.txt
+++ b/linter-requirements.txt
@@ -1,7 +1,10 @@
 black==22.3.0
 flake8==3.9.2
 flake8-import-order==0.18.1
-mypy==0.782
+mypy==0.950
+types-certifi
+types-redis
+types-setuptools
 flake8-bugbear==21.4.3
 pep8-naming==0.11.1
-pre-commit # local linting
\ No newline at end of file
+pre-commit # local linting
diff --git a/mypy.ini b/mypy.ini
index 7e30dddb5b..2a15e45e49 100644
--- a/mypy.ini
+++ b/mypy.ini
@@ -61,3 +61,5 @@ ignore_missing_imports = True
 disallow_untyped_defs = False
 [mypy-celery.app.trace]
 ignore_missing_imports = True
+[mypy-flask.signals]
+ignore_missing_imports = True
diff --git a/sentry_sdk/hub.py b/sentry_sdk/hub.py
index 22f3ff42fd..d2b57a2e45 100644
--- a/sentry_sdk/hub.py
+++ b/sentry_sdk/hub.py
@@ -117,7 +117,7 @@ def _init(*args, **kwargs):
     # Use `ClientConstructor` to define the argument types of `init` and
     # `ContextManager[Any]` to tell static analyzers about the return type.
 
-    class init(ClientConstructor, ContextManager[Any]):  # noqa: N801
+    class init(ClientConstructor, _InitGuard):  # noqa: N801
         pass
 
 else:
diff --git a/sentry_sdk/integrations/aws_lambda.py b/sentry_sdk/integrations/aws_lambda.py
index 0eae710bff..10b5025abe 100644
--- a/sentry_sdk/integrations/aws_lambda.py
+++ b/sentry_sdk/integrations/aws_lambda.py
@@ -302,12 +302,12 @@ def get_lambda_bootstrap():
         module = sys.modules["__main__"]
         # python3.9 runtime
         if hasattr(module, "awslambdaricmain") and hasattr(
-            module.awslambdaricmain, "bootstrap"  # type: ignore
+            module.awslambdaricmain, "bootstrap"
         ):
-            return module.awslambdaricmain.bootstrap  # type: ignore
+            return module.awslambdaricmain.bootstrap
         elif hasattr(module, "bootstrap"):
             # awslambdaric python module in container builds
-            return module.bootstrap  # type: ignore
+            return module.bootstrap
 
         # python3.8 runtime
         return module
diff --git a/sentry_sdk/integrations/celery.py b/sentry_sdk/integrations/celery.py
index 40a2dfbe39..743e2cfb50 100644
--- a/sentry_sdk/integrations/celery.py
+++ b/sentry_sdk/integrations/celery.py
@@ -23,7 +23,7 @@
 
 
 try:
-    from celery import VERSION as CELERY_VERSION  # type: ignore
+    from celery import VERSION as CELERY_VERSION
     from celery.exceptions import (  # type: ignore
         SoftTimeLimitExceeded,
         Retry,
diff --git a/sentry_sdk/integrations/excepthook.py b/sentry_sdk/integrations/excepthook.py
index 1e8597e13f..1f16ff0b06 100644
--- a/sentry_sdk/integrations/excepthook.py
+++ b/sentry_sdk/integrations/excepthook.py
@@ -10,11 +10,12 @@
     from typing import Callable
     from typing import Any
     from typing import Type
+    from typing import Optional
 
     from types import TracebackType
 
     Excepthook = Callable[
-        [Type[BaseException], BaseException, TracebackType],
+        [Type[BaseException], BaseException, Optional[TracebackType]],
         Any,
     ]
 
@@ -43,7 +44,7 @@ def setup_once():
 def _make_excepthook(old_excepthook):
     # type: (Excepthook) -> Excepthook
     def sentry_sdk_excepthook(type_, value, traceback):
-        # type: (Type[BaseException], BaseException, TracebackType) -> None
+        # type: (Type[BaseException], BaseException, Optional[TracebackType]) -> None
         hub = Hub.current
         integration = hub.get_integration(ExcepthookIntegration)
 
diff --git a/sentry_sdk/integrations/flask.py b/sentry_sdk/integrations/flask.py
index 8883cbb724..5aade50a94 100644
--- a/sentry_sdk/integrations/flask.py
+++ b/sentry_sdk/integrations/flask.py
@@ -94,7 +94,7 @@ def sentry_patched_wsgi_app(self, environ, start_response):
                 environ, start_response
             )
 
-        Flask.__call__ = sentry_patched_wsgi_app  # type: ignore
+        Flask.__call__ = sentry_patched_wsgi_app
 
 
 def _add_sentry_trace(sender, template, context, **extra):
diff --git a/sentry_sdk/integrations/gcp.py b/sentry_sdk/integrations/gcp.py
index e92422d8b9..118970e9d8 100644
--- a/sentry_sdk/integrations/gcp.py
+++ b/sentry_sdk/integrations/gcp.py
@@ -126,7 +126,7 @@ def __init__(self, timeout_warning=False):
     @staticmethod
     def setup_once():
         # type: () -> None
-        import __main__ as gcp_functions  # type: ignore
+        import __main__ as gcp_functions
 
         if not hasattr(gcp_functions, "worker_v1"):
             logger.warning(
diff --git a/sentry_sdk/integrations/logging.py b/sentry_sdk/integrations/logging.py
index 31c7b874ba..e9f3fe9dbb 100644
--- a/sentry_sdk/integrations/logging.py
+++ b/sentry_sdk/integrations/logging.py
@@ -78,7 +78,7 @@ def _handle_record(self, record):
     @staticmethod
     def setup_once():
         # type: () -> None
-        old_callhandlers = logging.Logger.callHandlers  # type: ignore
+        old_callhandlers = logging.Logger.callHandlers
 
         def sentry_patched_callhandlers(self, record):
             # type: (Any, LogRecord) -> Any
diff --git a/sentry_sdk/integrations/sqlalchemy.py b/sentry_sdk/integrations/sqlalchemy.py
index 3d10f2041e..deb97c05ad 100644
--- a/sentry_sdk/integrations/sqlalchemy.py
+++ b/sentry_sdk/integrations/sqlalchemy.py
@@ -70,7 +70,7 @@ def _after_cursor_execute(conn, cursor, statement, parameters, context, *args):
     # type: (Any, Any, Any, Any, Any, *Any) -> None
     ctx_mgr = getattr(
         context, "_sentry_sql_span_manager", None
-    )  # type: ContextManager[Any]
+    )  # type: Optional[ContextManager[Any]]
 
     if ctx_mgr is not None:
         context._sentry_sql_span_manager = None
@@ -93,7 +93,7 @@ def _handle_error(context, *args):
     # handler is going to be fatal.
     ctx_mgr = getattr(
         execution_context, "_sentry_sql_span_manager", None
-    )  # type: ContextManager[Any]
+    )  # type: Optional[ContextManager[Any]]
 
     if ctx_mgr is not None:
         execution_context._sentry_sql_span_manager = None
diff --git a/sentry_sdk/integrations/stdlib.py b/sentry_sdk/integrations/stdlib.py
index adea742b2d..9495d406dc 100644
--- a/sentry_sdk/integrations/stdlib.py
+++ b/sentry_sdk/integrations/stdlib.py
@@ -157,7 +157,7 @@ def sentry_patched_popen_init(self, *a, **kw):
 
         hub = Hub.current
         if hub.get_integration(StdlibIntegration) is None:
-            return old_popen_init(self, *a, **kw)  # type: ignore
+            return old_popen_init(self, *a, **kw)
 
         # Convert from tuple to list to be able to set values.
         a = list(a)
@@ -195,7 +195,7 @@ def sentry_patched_popen_init(self, *a, **kw):
             if cwd:
                 span.set_data("subprocess.cwd", cwd)
 
-            rv = old_popen_init(self, *a, **kw)  # type: ignore
+            rv = old_popen_init(self, *a, **kw)
 
             span.set_tag("subprocess.pid", self.pid)
             return rv
diff --git a/sentry_sdk/integrations/threading.py b/sentry_sdk/integrations/threading.py
index b750257e2a..f29e5e8797 100644
--- a/sentry_sdk/integrations/threading.py
+++ b/sentry_sdk/integrations/threading.py
@@ -51,7 +51,7 @@ def sentry_start(self, *a, **kw):
                     new_run = _wrap_run(hub_, getattr(self.run, "__func__", self.run))
                     self.run = new_run  # type: ignore
 
-            return old_start(self, *a, **kw)  # type: ignore
+            return old_start(self, *a, **kw)
 
         Thread.start = sentry_start  # type: ignore
 
diff --git a/sentry_sdk/integrations/tornado.py b/sentry_sdk/integrations/tornado.py
index f9796daca3..443ebefaa8 100644
--- a/sentry_sdk/integrations/tornado.py
+++ b/sentry_sdk/integrations/tornado.py
@@ -21,7 +21,7 @@
 from sentry_sdk._compat import iteritems
 
 try:
-    from tornado import version_info as TORNADO_VERSION  # type: ignore
+    from tornado import version_info as TORNADO_VERSION
     from tornado.web import RequestHandler, HTTPError
     from tornado.gen import coroutine
 except ImportError:
@@ -58,7 +58,7 @@ def setup_once():
 
         ignore_logger("tornado.access")
 
-        old_execute = RequestHandler._execute  # type: ignore
+        old_execute = RequestHandler._execute
 
         awaitable = iscoroutinefunction(old_execute)
 
@@ -79,16 +79,16 @@ def sentry_execute_request_handler(self, *args, **kwargs):  # type: ignore
                     result = yield from old_execute(self, *args, **kwargs)
                     return result
 
-        RequestHandler._execute = sentry_execute_request_handler  # type: ignore
+        RequestHandler._execute = sentry_execute_request_handler
 
         old_log_exception = RequestHandler.log_exception
 
         def sentry_log_exception(self, ty, value, tb, *args, **kwargs):
             # type: (Any, type, BaseException, Any, *Any, **Any) -> Optional[Any]
             _capture_exception(ty, value, tb)
-            return old_log_exception(self, ty, value, tb, *args, **kwargs)  # type: ignore
+            return old_log_exception(self, ty, value, tb, *args, **kwargs)
 
-        RequestHandler.log_exception = sentry_log_exception  # type: ignore
+        RequestHandler.log_exception = sentry_log_exception
 
 
 @contextlib.contextmanager
@@ -105,7 +105,7 @@ def _handle_request_impl(self):
     with Hub(hub) as hub:
         with hub.configure_scope() as scope:
             scope.clear_breadcrumbs()
-            processor = _make_event_processor(weak_handler)  # type: ignore
+            processor = _make_event_processor(weak_handler)
             scope.add_event_processor(processor)
 
         transaction = Transaction.continue_from_headers(
@@ -155,7 +155,7 @@ def tornado_processor(event, hint):
         request = handler.request
 
         with capture_internal_exceptions():
-            method = getattr(handler, handler.request.method.lower())  # type: ignore
+            method = getattr(handler, handler.request.method.lower())
             event["transaction"] = transaction_from_function(method)
 
         with capture_internal_exceptions():
diff --git a/sentry_sdk/utils.py b/sentry_sdk/utils.py
index e22f6ae065..0a735a1e20 100644
--- a/sentry_sdk/utils.py
+++ b/sentry_sdk/utils.py
@@ -171,7 +171,7 @@ def __init__(self, value):
         self.host = parts.hostname
 
         if parts.port is None:
-            self.port = self.scheme == "https" and 443 or 80
+            self.port = self.scheme == "https" and 443 or 80  # type: int
         else:
             self.port = parts.port
 
@@ -466,6 +466,9 @@ def filename_for_module(module, abs_path):
             return os.path.basename(abs_path)
 
         base_module_path = sys.modules[base_module].__file__
+        if not base_module_path:
+            return abs_path
+
         return abs_path.split(base_module_path.rsplit(os.sep, 2)[0], 1)[-1].lstrip(
             os.sep
         )
diff --git a/tox.ini b/tox.ini
index 2cdf8a45bf..0ca43ab8a2 100644
--- a/tox.ini
+++ b/tox.ini
@@ -324,4 +324,4 @@ commands =
 commands =
     flake8 tests examples sentry_sdk
     black --check tests examples sentry_sdk
-    mypy examples sentry_sdk
+    mypy sentry_sdk