diff --git a/sentry_sdk/client.py b/sentry_sdk/client.py
index 628cb00ee3..63a1205f57 100644
--- a/sentry_sdk/client.py
+++ b/sentry_sdk/client.py
@@ -48,6 +48,9 @@ def _get_options(*args, **kwargs):
     else:
         dsn = None
 
+    if len(args) > 1:
+        raise TypeError("Only single positional argument is expected")
+
     rv = dict(DEFAULT_OPTIONS)
     options = dict(*args, **kwargs)
     if dsn is not None and options.get("dsn") is None:
diff --git a/tests/test_client.py b/tests/test_client.py
index c8dd6955fe..ffdb831e39 100644
--- a/tests/test_client.py
+++ b/tests/test_client.py
@@ -887,3 +887,9 @@ def test_max_breadcrumbs_option(
     capture_message("dogs are great")
 
     assert len(events[0]["breadcrumbs"]["values"]) == expected_breadcrumbs
+
+
+def test_multiple_positional_args(sentry_init):
+    with pytest.raises(TypeError) as exinfo:
+        sentry_init(1, None)
+    assert "Only single positional argument is expected" in str(exinfo.value)