diff --git a/lib/sidekiq.rb b/lib/sidekiq.rb
index 3ee4f9d26a..6f5d3c80f7 100644
--- a/lib/sidekiq.rb
+++ b/lib/sidekiq.rb
@@ -100,7 +100,8 @@ def self.redis
         # 2550 Failover can cause the server to become a replica, need
         # to disconnect and reopen the socket to get back to the primary.
         # 4495 Use the same logic if we have a "Not enough replicas" error from the primary
-        if retryable && ex.message =~ /READONLY|NOREPLICAS/
+        # 4985 Use the same logic when a blocking command is force-unblocked
+        if retryable && ex.message =~ /READONLY|NOREPLICAS|master -> replica/
           conn.disconnect!
           retryable = false
           retry
diff --git a/test/test_sidekiq.rb b/test/test_sidekiq.rb
index 7a1c625651..1852a6261b 100644
--- a/test/test_sidekiq.rb
+++ b/test/test_sidekiq.rb
@@ -96,6 +96,16 @@
       assert_equal 2, counts.size
       assert_equal counts[0] + 1, counts[1]
     end
+
+    it 'reconnects if instance state changed' do
+      counts = []
+      Sidekiq.redis do |c|
+        counts << c.info['total_connections_received'].to_i
+        raise Redis::CommandError, "UNBLOCKED force unblock from blocking operation, instance state changed (master -> replica?)" if counts.size == 1
+      end
+      assert_equal 2, counts.size
+      assert_equal counts[0] + 1, counts[1]
+    end
   end
 
   describe 'redis info' do