diff --git a/flask_cors/core.py b/flask_cors/core.py
index c46f72d..09150ea 100644
--- a/flask_cors/core.py
+++ b/flask_cors/core.py
@@ -246,9 +246,10 @@ def probably_regex(maybe_regex):
     if isinstance(maybe_regex, RegexObject):
         return True
     else:
+        common_regex_chars = ['*','\\',']', '?']
         # Use common characters used in regular expressions as a proxy
         # for if this string is in fact a regex.
-        return any((c in maybe_regex for c in ['*','\\',']']))
+        return any((c in maybe_regex for c in common_regex_chars))
 
 def re_fix(reg):
     """
diff --git a/tests/core/helper_tests.py b/tests/core/helper_tests.py
index 5501ff8..ce71e6a 100644
--- a/tests/core/helper_tests.py
+++ b/tests/core/helper_tests.py
@@ -90,3 +90,4 @@ def test_probably_regex(self):
         self.assertFalse(probably_regex("http://example.com"))
         self.assertTrue(probably_regex("http://[\w].example.com"))
         self.assertTrue(probably_regex("http://\w+.example.com"))
+        self.assertTrue(probably_regex("https?://example.com"))
diff --git a/tests/decorator/test_origins.py b/tests/decorator/test_origins.py
index 743dd3c..099b2ff 100644
--- a/tests/decorator/test_origins.py
+++ b/tests/decorator/test_origins.py
@@ -76,6 +76,11 @@ def test_regex_list():
         def test_regex_mixed_list():
             return ''
 
+        @self.app.route('/test_multiple_protocols')
+        @cross_origin(origins="https?://example.com")
+        def test_multiple_protocols():
+            return ''
+
     def test_defaults_no_origin(self):
         ''' If there is no Origin header in the request, the
             Access-Control-Allow-Origin header should be '*' by default.
@@ -188,6 +193,12 @@ def test_regex_mixed_list(self):
         self.assertEquals("http://example.com",
             self.get('/test_regex_mixed_list', origin='http://example.com').headers.get(ACL_ORIGIN))
 
+    def test_multiple_protocols(self):
+        import logging
+        logging.getLogger('flask_cors').level = logging.DEBUG
+        resp = self.get('test_multiple_protocols', origin='https://example.com')
+        self.assertEqual('https://example.com', resp.headers.get(ACL_ORIGIN))
+
 
 if __name__ == "__main__":
     unittest.main()