diff --git a/bentoml/_internal/io_descriptors/numpy.py b/bentoml/_internal/io_descriptors/numpy.py
index 151f1b53c5d..d860a6da376 100644
--- a/bentoml/_internal/io_descriptors/numpy.py
+++ b/bentoml/_internal/io_descriptors/numpy.py
@@ -223,7 +223,7 @@ def __init__(
         enforce_dtype: bool = False,
         shape: tuple[int, ...] | None = None,
         enforce_shape: bool = False,
-        packed: bool = True,
+        packed: bool = False,
         bytesorder: t.Literal["C", "F", "A", None] = None,
     ):
         if dtype is not None and not isinstance(dtype, np.dtype):
@@ -441,6 +441,7 @@ async def to_grpc_response(
                 Protobuf representation of given `np.ndarray`
         """
         from ..utils.grpc import grpc_status_code
+        from ..configuration import get_debug_mode
 
         _NPTYPE_TO_DTYPE_STRING_MAP = {
             np.dtype(v): k for k, v in _DTYPE_TO_STRING_MAP.items()
@@ -460,6 +461,10 @@ async def to_grpc_response(
         if self._packed:
             cnt.update({"bytes_contents": obj.tobytes(order=self._bytesorder)})
         else:
+            if self._bytesorder:
+                logger.warning(
+                    f"'bytesorder={self._bytesorder}' is ignored when 'packed={self._packed}'."
+                )
             cnt.update({_DTYPE_TO_FIELD_MAP[dtype_string]: obj.tolist()})
 
         if obj.ndim == 1:
@@ -472,6 +477,8 @@ async def to_grpc_response(
                     shape=tuple(obj.shape), array=service_pb2.Array(**cnt)
                 )
             )
+        if get_debug_mode():
+            logger.debug(f"Response proto: \n{resp}")
         return resp
 
     def generate_protobuf(self):
diff --git a/bentoml/_internal/server/grpc/servicer.py b/bentoml/_internal/server/grpc/servicer.py
index 5d0109333a7..5ff5977d760 100644
--- a/bentoml/_internal/server/grpc/servicer.py
+++ b/bentoml/_internal/server/grpc/servicer.py
@@ -3,6 +3,7 @@
 import asyncio
 from typing import TYPE_CHECKING
 
+import anyio
 from grpc import aio
 
 from bentoml.exceptions import UnprocessableEntity
@@ -41,7 +42,7 @@ async def Infer(  # type: ignore (no async types)
             if asyncio.iscoroutinefunction(api.func):
                 output = await api.func(input)
             else:
-                output = api.func(input)
+                output = await anyio.to_thread.run_sync(api.func, input)
 
             return await api.output.to_grpc_response(output, context)