diff --git a/packages/babel-helper-module-transforms/src/rewrite-live-references.ts b/packages/babel-helper-module-transforms/src/rewrite-live-references.ts
index 11c956aa8748..ca7b3e36e531 100644
--- a/packages/babel-helper-module-transforms/src/rewrite-live-references.ts
+++ b/packages/babel-helper-module-transforms/src/rewrite-live-references.ts
@@ -44,6 +44,25 @@ interface RewriteBindingInitVisitorState {
   scope: Scope;
 }
 
+function isInType(path) {
+  do {
+    switch (path.parent.type) {
+      case "TSTypeAnnotation":
+      case "TSTypeAliasDeclaration":
+      case "TSTypeReference":
+      case "TypeAnnotation":
+      case "TypeAlias":
+        return true;
+      case "ExportSpecifier":
+        return path.parentPath.parent.exportKind === "type";
+      default:
+        if (path.parentPath.isStatement() || path.parentPath.isExpression()) {
+          return false;
+        }
+    }
+  } while ((path = path.parentPath));
+}
+
 export default function rewriteLiveReferences(
   programPath: NodePath<t.Program>,
   metadata: ModuleMetadata,
@@ -224,6 +243,13 @@ const rewriteReferencesVisitor: Visitor<RewriteReferencesVisitorState> = {
 
     const importData = imported.get(localName);
     if (importData) {
+      if (isInType(path)) {
+        throw path.buildCodeFrameError(
+          `Cannot transform the imported binding "${localName}" since it's also used in a type annotation. ` +
+            `Please strip type annotations using @babel/preset-typescript or @babel/preset-flow.`,
+        );
+      }
+
       const localBinding = path.scope.getBinding(localName);
       const rootBinding = scope.getBinding(localName);
 
diff --git a/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin-deep/input.js b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin-deep/input.js
new file mode 100644
index 000000000000..a2fc7f67c62b
--- /dev/null
+++ b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin-deep/input.js
@@ -0,0 +1,5 @@
+import A from "x";
+
+export function fn(x: A.b[2]) {
+  return A.method(x);
+}
diff --git a/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin-deep/options.json b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin-deep/options.json
new file mode 100644
index 000000000000..f67526e40e72
--- /dev/null
+++ b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin-deep/options.json
@@ -0,0 +1,6 @@
+{
+  "externalHelpers": true,
+  "sourceType": "module",
+  "plugins": ["transform-modules-commonjs", "syntax-flow"],
+  "throws": "Cannot transform the imported binding \"A\" since it's also used in a type annotation. Please strip type annotations using @babel/preset-typescript or @babel/preset-flow."
+}
diff --git a/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin-type-cast/input.js b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin-type-cast/input.js
new file mode 100644
index 000000000000..8bc03f2248ae
--- /dev/null
+++ b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin-type-cast/input.js
@@ -0,0 +1,3 @@
+import { A } from "x";
+
+var x = ({} : A.b[0]);
diff --git a/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin-type-cast/options.json b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin-type-cast/options.json
new file mode 100644
index 000000000000..f67526e40e72
--- /dev/null
+++ b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin-type-cast/options.json
@@ -0,0 +1,6 @@
+{
+  "externalHelpers": true,
+  "sourceType": "module",
+  "plugins": ["transform-modules-commonjs", "syntax-flow"],
+  "throws": "Cannot transform the imported binding \"A\" since it's also used in a type annotation. Please strip type annotations using @babel/preset-typescript or @babel/preset-flow."
+}
diff --git a/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin/input.js b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin/input.js
new file mode 100644
index 000000000000..2d646ec1b207
--- /dev/null
+++ b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin/input.js
@@ -0,0 +1,5 @@
+import A from "x";
+
+export function fn(x: A) {
+  return A.method(x);
+}
diff --git a/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin/options.json b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin/options.json
new file mode 100644
index 000000000000..f67526e40e72
--- /dev/null
+++ b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-flow-plugin/options.json
@@ -0,0 +1,6 @@
+{
+  "externalHelpers": true,
+  "sourceType": "module",
+  "plugins": ["transform-modules-commonjs", "syntax-flow"],
+  "throws": "Cannot transform the imported binding \"A\" since it's also used in a type annotation. Please strip type annotations using @babel/preset-typescript or @babel/preset-flow."
+}
diff --git a/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-deep/input.ts b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-deep/input.ts
new file mode 100644
index 000000000000..a2fc7f67c62b
--- /dev/null
+++ b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-deep/input.ts
@@ -0,0 +1,5 @@
+import A from "x";
+
+export function fn(x: A.b[2]) {
+  return A.method(x);
+}
diff --git a/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-deep/options.json b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-deep/options.json
new file mode 100644
index 000000000000..343fffdf6f9c
--- /dev/null
+++ b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-deep/options.json
@@ -0,0 +1,6 @@
+{
+  "externalHelpers": true,
+  "sourceType": "module",
+  "plugins": ["transform-modules-commonjs", "syntax-typescript"],
+  "throws": "Cannot transform the imported binding \"A\" since it's also used in a type annotation. Please strip type annotations using @babel/preset-typescript or @babel/preset-flow."
+}
diff --git a/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-type-assertion-legacy/input.ts b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-type-assertion-legacy/input.ts
new file mode 100644
index 000000000000..6bf00bc3a8b0
--- /dev/null
+++ b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-type-assertion-legacy/input.ts
@@ -0,0 +1,3 @@
+import { A } from "x";
+
+var x = {} as A.b[0];
diff --git a/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-type-assertion-legacy/options.json b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-type-assertion-legacy/options.json
new file mode 100644
index 000000000000..343fffdf6f9c
--- /dev/null
+++ b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-type-assertion-legacy/options.json
@@ -0,0 +1,6 @@
+{
+  "externalHelpers": true,
+  "sourceType": "module",
+  "plugins": ["transform-modules-commonjs", "syntax-typescript"],
+  "throws": "Cannot transform the imported binding \"A\" since it's also used in a type annotation. Please strip type annotations using @babel/preset-typescript or @babel/preset-flow."
+}
diff --git a/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-type-assertion/input.ts b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-type-assertion/input.ts
new file mode 100644
index 000000000000..f046a912385b
--- /dev/null
+++ b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-type-assertion/input.ts
@@ -0,0 +1,3 @@
+import { A } from "x";
+
+var x = <A.b[0]> {};
diff --git a/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-type-assertion/options.json b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-type-assertion/options.json
new file mode 100644
index 000000000000..343fffdf6f9c
--- /dev/null
+++ b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin-type-assertion/options.json
@@ -0,0 +1,6 @@
+{
+  "externalHelpers": true,
+  "sourceType": "module",
+  "plugins": ["transform-modules-commonjs", "syntax-typescript"],
+  "throws": "Cannot transform the imported binding \"A\" since it's also used in a type annotation. Please strip type annotations using @babel/preset-typescript or @babel/preset-flow."
+}
diff --git a/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin/input.ts b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin/input.ts
new file mode 100644
index 000000000000..2d646ec1b207
--- /dev/null
+++ b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin/input.ts
@@ -0,0 +1,5 @@
+import A from "x";
+
+export function fn(x: A) {
+  return A.method(x);
+}
diff --git a/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin/options.json b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin/options.json
new file mode 100644
index 000000000000..343fffdf6f9c
--- /dev/null
+++ b/packages/babel-plugin-transform-modules-commonjs/test/fixtures/integration/missing-ts-plugin/options.json
@@ -0,0 +1,6 @@
+{
+  "externalHelpers": true,
+  "sourceType": "module",
+  "plugins": ["transform-modules-commonjs", "syntax-typescript"],
+  "throws": "Cannot transform the imported binding \"A\" since it's also used in a type annotation. Please strip type annotations using @babel/preset-typescript or @babel/preset-flow."
+}