diff --git a/packages/babel-plugin-transform-destructuring/src/index.js b/packages/babel-plugin-transform-destructuring/src/index.js
index 814ff169ee92..7af938dbeb28 100644
--- a/packages/babel-plugin-transform-destructuring/src/index.js
+++ b/packages/babel-plugin-transform-destructuring/src/index.js
@@ -190,7 +190,7 @@ export default declare((api, options) => {
 
       const keys = [];
       let allLiteral = true;
-
+      let hasTemplateLiteral = false;
       for (let i = 0; i < pattern.properties.length; i++) {
         const prop = pattern.properties[i];
 
@@ -204,8 +204,9 @@ export default declare((api, options) => {
         const key = prop.key;
         if (t.isIdentifier(key) && !prop.computed) {
           keys.push(t.stringLiteral(key.name));
-        } else if (t.isTemplateLiteral(prop.key)) {
-          keys.push(t.cloneNode(prop.key));
+        } else if (t.isTemplateLiteral(key)) {
+          keys.push(t.cloneNode(key));
+          hasTemplateLiteral = true;
         } else if (t.isLiteral(key)) {
           keys.push(t.stringLiteral(String(key.value)));
         } else {
@@ -228,7 +229,7 @@ export default declare((api, options) => {
             t.memberExpression(keyExpression, t.identifier("map")),
             [this.addHelper("toPropertyKey")],
           );
-        } else if (!t.isProgram(this.scope.block)) {
+        } else if (!hasTemplateLiteral && !t.isProgram(this.scope.block)) {
           // Hoist definition of excluded keys, so that it's not created each time.
           const program = this.scope.path.findParent(path => path.isProgram());
           const id = this.scope.generateUidIdentifier("excluded");
diff --git a/packages/babel-plugin-transform-destructuring/test/fixtures/destructuring/check-no-hoisting-when-using-template-strings/input.js b/packages/babel-plugin-transform-destructuring/test/fixtures/destructuring/check-no-hoisting-when-using-template-strings/input.js
new file mode 100644
index 000000000000..bf5b80eb1bee
--- /dev/null
+++ b/packages/babel-plugin-transform-destructuring/test/fixtures/destructuring/check-no-hoisting-when-using-template-strings/input.js
@@ -0,0 +1,4 @@
+const example = (obj) => {
+  const foo = 'foo';
+  const { [`prefix_${foo}`]: _, ...rest } = obj;
+};
diff --git a/packages/babel-plugin-transform-destructuring/test/fixtures/destructuring/check-no-hoisting-when-using-template-strings/output.js b/packages/babel-plugin-transform-destructuring/test/fixtures/destructuring/check-no-hoisting-when-using-template-strings/output.js
new file mode 100644
index 000000000000..000d34966b47
--- /dev/null
+++ b/packages/babel-plugin-transform-destructuring/test/fixtures/destructuring/check-no-hoisting-when-using-template-strings/output.js
@@ -0,0 +1,5 @@
+var example = obj => {
+  var foo = 'foo';
+  var _ = obj[`prefix_${foo}`],
+      rest = babelHelpers.objectWithoutProperties(obj, [`prefix_${foo}`]);
+};