diff --git a/packages/babel-plugin-transform-react-jsx/src/create-plugin.ts b/packages/babel-plugin-transform-react-jsx/src/create-plugin.ts
index 0fa5a3810452..982083f1671e 100644
--- a/packages/babel-plugin-transform-react-jsx/src/create-plugin.ts
+++ b/packages/babel-plugin-transform-react-jsx/src/create-plugin.ts
@@ -32,12 +32,11 @@ const DEFAULT = {
 };
 
 const JSX_SOURCE_ANNOTATION_REGEX =
-  /^\*?\s*?\*?\*?\s*@jsxImportSource\s+([^\s]+)\s*$/;
-const JSX_RUNTIME_ANNOTATION_REGEX =
-  /^\*?\s*?\*?\*?\s*@jsxRuntime\s+([^\s]+)\s*$/;
+  /^\s*\*?\s*@jsxImportSource\s+([^\s]+)\s*$/m;
+const JSX_RUNTIME_ANNOTATION_REGEX = /^\s*\*?\s*@jsxRuntime\s+([^\s]+)\s*$/m;
 
-const JSX_ANNOTATION_REGEX = /^\*?\s*?\*?\*?\s*@jsx\s+([^\s]+)\s*$/;
-const JSX_FRAG_ANNOTATION_REGEX = /^\*?\s*?\*?\*?\s*@jsxFrag\s+([^\s]+)\s*$/;
+const JSX_ANNOTATION_REGEX = /^\s*\*?\s*@jsx\s+([^\s]+)\s*$/m;
+const JSX_FRAG_ANNOTATION_REGEX = /^\s*\*?\s*@jsxFrag\s+([^\s]+)\s*$/m;
 
 const get = (pass: PluginPass, name: string) =>
   pass.get(`@babel/plugin-react-jsx/${name}`);