diff --git a/setup.py b/setup.py
index 4070543a7..76eceb455 100644
--- a/setup.py
+++ b/setup.py
@@ -385,7 +385,7 @@ def _populate_hdf5_info(dirstosearch, inc_dirs, libs, lib_dirs):
     dirstosearch.append(os.environ["CONDA_PREFIX"]) # linux,macosx
     dirstosearch.append(os.path.join(os.environ["CONDA_PREFIX"],'Library')) # windows
 dirstosearch += [os.path.expanduser('~'), '/usr/local', '/sw', '/opt',
-                '/opt/local', '/usr']
+                '/opt/local', '/opt/homebrew', '/usr']
 
 # try nc-config first
 if USE_NCCONFIG and HAS_NCCONFIG:  # Try nc-config.