diff --git a/CHANGELOG.md b/CHANGELOG.md
index 4ba31082c..dc51d2278 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -6,6 +6,7 @@ Find out more about isort's release policy [here](https://pycqa.github.io/isort/
 
 ### 5.9.2 TBD
   - Improved behavior of `isort --check --atomic` against Cython files.
+  - Fixed #1769: Future imports added below assignments when no other imports present.
   - Fixed #1772: skip-gitignore will check files not in the git repository.
   - Fixed #1762: in some cases when skip-gitignore is set, isort fails to skip any files.
 
diff --git a/isort/core.py b/isort/core.py
index 7b2910da5..4b24e45cd 100644
--- a/isort/core.py
+++ b/isort/core.py
@@ -55,6 +55,7 @@ def process(
     next_import_section: str = ""
     next_cimports: bool = False
     in_quote: str = ""
+    was_in_quote: bool = False
     first_comment_index_start: int = -1
     first_comment_index_end: int = -1
     contains_imports: bool = False
@@ -332,14 +333,15 @@ def process(
                 and (stripped_line or end_of_file)
                 and not config.append_only
                 and not in_top_comment
-                and not in_quote
+                and not was_in_quote
                 and not import_section
                 and not line.lstrip().startswith(COMMENT_INDICATORS)
-                and not line.rstrip().endswith(DOCSTRING_INDICATORS)
+                and not (line.rstrip().endswith(DOCSTRING_INDICATORS) and "=" not in line)
             ):
-                import_section = line_separator.join(add_imports) + line_separator
+                add_line_separator = line_separator or "\n"
+                import_section = add_line_separator.join(add_imports) + add_line_separator
                 if end_of_file and index != 0:
-                    output_stream.write(line_separator)
+                    output_stream.write(add_line_separator)
                 contains_imports = True
                 add_imports = []
 
diff --git a/tests/unit/test_regressions.py b/tests/unit/test_regressions.py
index 388aa8d38..449f83d53 100644
--- a/tests/unit/test_regressions.py
+++ b/tests/unit/test_regressions.py
@@ -1798,3 +1798,33 @@ def test_isort_should_keep_multiple_noqa_comments_force_single_line_mode_issue_1
         profile="black",
         force_single_line=True,
     )
+
+
+def test_isort_should_only_add_imports_to_valid_location_issue_1769():
+    assert (
+        isort.code(
+            '''v = """
+""".split(
+    "\n"
+)
+''',
+            add_imports=["from __future__ import annotations"],
+        )
+        == '''from __future__ import annotations
+
+v = """
+""".split(
+    "\n"
+)
+'''
+    )
+    assert (
+        isort.code(
+            '''v=""""""''',
+            add_imports=["from __future__ import annotations"],
+        )
+        == '''from __future__ import annotations
+
+v=""""""
+'''
+    )