diff --git a/doc/whatsnew/2/2.14/full.rst b/doc/whatsnew/2/2.14/full.rst
index edc5fa4c7e..e98432e115 100644
--- a/doc/whatsnew/2/2.14/full.rst
+++ b/doc/whatsnew/2/2.14/full.rst
@@ -17,6 +17,10 @@ Release date: TBA
 
 * Fixed the disabling of ``fixme`` and its interaction with ``useless-suppression``.
 
+* Allow lists of default values in parameter documentation for ``Numpy`` style.
+
+  Closes #4035
+
 
 What's New in Pylint 2.14.4?
 ----------------------------
diff --git a/pylint/extensions/_check_docs_utils.py b/pylint/extensions/_check_docs_utils.py
index dacdbe05ee..d8bf22e228 100644
--- a/pylint/extensions/_check_docs_utils.py
+++ b/pylint/extensions/_check_docs_utils.py
@@ -727,11 +727,22 @@ class NumpyDocstring(GoogleDocstring):
         re.X | re.S | re.M,
     )
 
+    re_default_value = r"""((['"]\w+\s*['"])|(True)|(False)|(None))"""
+
     re_param_line = re.compile(
         rf"""
-        \s*  (\*{{0,2}}\w+)(\s?(:|\n))                                      # identifier with potential asterisks
-        \s*  (?:({GoogleDocstring.re_multiple_type})(?:,\s+optional)?\n)?   # optional type declaration
-        \s* (.*)                                                            # optional description
+        \s*  (\*{{0,2}}\w+)(\s?(:|\n))              # identifier with potential asterisks
+        \s*
+        (
+         (
+          ({GoogleDocstring.re_multiple_type})      # default type declaration
+          (,\s+optional)?                           # optional 'optional' indication
+         )?
+         (
+          {{({re_default_value},?\s*)+}}            # set of default values
+         )?
+        \n)?
+        \s* (.*)                                    # optional description
     """,
         re.X | re.S,
     )
diff --git a/tests/functional/ext/docparams/parameter/missing_param_doc_required_Numpy.py b/tests/functional/ext/docparams/parameter/missing_param_doc_required_Numpy.py
index c47d03c316..6e725980fb 100644
--- a/tests/functional/ext/docparams/parameter/missing_param_doc_required_Numpy.py
+++ b/tests/functional/ext/docparams/parameter/missing_param_doc_required_Numpy.py
@@ -391,3 +391,18 @@ def test_ignores_optional_specifier_numpy(param, param2="all"):
         Description.
     """
     return param, param2
+
+def test_with_list_of_default_values(arg, option, option2):
+    """Reported in https://github.com/PyCQA/pylint/issues/4035.
+
+    Parameters
+    ----------
+    arg : int
+        The number of times to print it.
+    option : {"y", "n"}
+        Do I do it?
+    option2 : {"y", None, "n"}
+        Do I do it?
+
+    """
+    return arg, option, option2