diff --git a/ChangeLog b/ChangeLog
index 043639dc52d..aed43aa9f0b 100644
--- a/ChangeLog
+++ b/ChangeLog
@@ -45,6 +45,10 @@ Release date: TBA
 
 * Fix false positive for ``protected-access`` if a protected member is used in type hints of function definitions
 
+* Fix false positive ``dict-iter-missing-items`` for dictionaries only using tuples as keys
+
+  Closes #3282
+
 
 What's New in Pylint 2.10.3?
 ============================
diff --git a/doc/whatsnew/2.11.rst b/doc/whatsnew/2.11.rst
index 8524c0a900e..e91199fb02a 100644
--- a/doc/whatsnew/2.11.rst
+++ b/doc/whatsnew/2.11.rst
@@ -51,3 +51,7 @@ Other Changes
   Closes #4936
 
 * Fix false positive for ``protected-access`` if a protected member is used in type hints of function definitions
+
+* Fix false positive ``dict-iter-missing-items`` for dictionaries only using tuples as keys
+
+  Closes #3282
diff --git a/pylint/checkers/typecheck.py b/pylint/checkers/typecheck.py
index 54a47057a8f..a79d2fa6b0c 100644
--- a/pylint/checkers/typecheck.py
+++ b/pylint/checkers/typecheck.py
@@ -1862,6 +1862,10 @@ def visit_for(self, node):
             # the iterable is not a dict
             return
 
+        if all(isinstance(i[0], nodes.Tuple) for i in inferred.items):
+            # if all keys are tuples
+            return
+
         self.add_message("dict-iter-missing-items", node=node)
 
 
diff --git a/tests/functional/d/dict_iter_missing_items.py b/tests/functional/d/dict_iter_missing_items.py
index 333f5899087..81977b0267b 100644
--- a/tests/functional/d/dict_iter_missing_items.py
+++ b/tests/functional/d/dict_iter_missing_items.py
@@ -2,6 +2,7 @@
 from unknown import Uninferable
 
 d = {1: 1, 2: 2}
+d_tuple = {(1, 2): 3, (4, 5): 6}
 l = [1, 2]
 s1 = {1, 2}
 s2 = {1, 2, 3}
@@ -21,3 +22,5 @@
     pass
 for k, v in Uninferable:
     pass
+for a, b in d_tuple:
+    pass
diff --git a/tests/functional/d/dict_iter_missing_items.txt b/tests/functional/d/dict_iter_missing_items.txt
index 3e1ed808c00..c3eb12f2c99 100644
--- a/tests/functional/d/dict_iter_missing_items.txt
+++ b/tests/functional/d/dict_iter_missing_items.txt
@@ -1 +1 @@
-dict-iter-missing-items:10:0::Unpacking a dictionary in iteration without calling .items()
+dict-iter-missing-items:11:0::Unpacking a dictionary in iteration without calling .items()